CRCGN012_HEPG2_24H:B06 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
6.90687
|
|
UBQLN2
|
ubiquilin 2
|
6.43701
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.9092
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.44088
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
4.63905
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.45457
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.09896
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.82958
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.5285
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.42088
|
|
TBXA2R
|
thromboxane A2 receptor
|
3.38983
|
|
SMIM40
|
small integral membrane protein 40
|
3.36708
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.24179
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.13173
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.10034
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.87451
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.83868
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.74408
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.70743
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.54628
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.48217
|
|
TLR4
|
toll-like receptor 4
|
2.29415
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.17203
|
|
VGLL4
|
vestigial-like family member 4
|
2.14713
|
|
HEBP1
|
heme binding protein 1
|
2.1245
|
|
MOK
|
MOK protein kinase
|
2.08388
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
-6.14509
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.81389
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.59563
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.56115
|
|
CDC20
|
cell division cycle 20
|
-3.54709
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.31986
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.207
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.10564
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.10269
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.94664
|
|
WASHC4
|
WASH complex subunit 4
|
-2.82481
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.59735
|
|
CDC25B
|
cell division cycle 25B
|
-2.59626
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.50959
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.48523
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.42137
|
|
LGMN
|
legumain
|
-2.31201
|
|
EGF
|
epidermal growth factor
|
-2.13587
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.10417
|
|
FAT2
|
FAT atypical cadherin 2
|
-2.00976
|
