CRCGN012_HEPG2_24H:B07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumarin 40.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

38 genes differentially expressed following the CRCGN012_HEPG2_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO1 anoctamin 1, calcium activated chloride channel 6.99854
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.89328
CSK c-src tyrosine kinase 5.89239
ADRB2 adrenoceptor beta 2, surface 3.91318
STK10 serine/threonine kinase 10 3.82244
TIAM1 T-cell lymphoma invasion and metastasis 1 3.75845
ALDOC aldolase C, fructose-bisphosphate 3.23525
PPARG peroxisome proliferator-activated receptor gamma 2.9207
SNAP25 synaptosomal-associated protein, 25kDa 2.85279
ATP11B ATPase, class VI, type 11B 2.76178
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.74239
PRR15L proline rich 15-like 2.66932
EPHA3 EPH receptor A3 2.61053
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.57311
ADGRE5 adhesion G protein-coupled receptor E5 2.50943
STIMATE STIM activating enhancer 2.49562
EVL Enah/Vasp-like 2.44746
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.42388
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.32229
RALGDS ral guanine nucleotide dissociation stimulator 2.20905
DIPK1A divergent protein kinase domain 1A 2.20316
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.16159
GPER1 G protein-coupled estrogen receptor 1 2.10116
KLHL9 kelch-like family member 9 2.04528

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.17873
CCNB2 cyclin B2 -3.89654
FBXL12 F-box and leucine-rich repeat protein 12 -3.78367
UGDH UDP-glucose 6-dehydrogenase -3.60588
FGFR4 fibroblast growth factor receptor 4 -2.8917
PLK1 polo-like kinase 1 -2.81648
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.72859
CD320 CD320 molecule -2.62213
SLC35F2 solute carrier family 35, member F2 -2.6032
LDHD lactate dehydrogenase D -2.48157
PRPF4 pre-mRNA processing factor 4 -2.2054
PRAF2 PRA1 domain family, member 2 -2.12549
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.09132
XPO7 exportin 7 -2.05243