CRCGN012_HEPG2_24H:B09 Gene Set
Genes
45 genes differentially expressed following the CRCGN012_HEPG2_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
7.17171
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
6.39859
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.84921
|
|
TBPL1
|
TBP-like 1
|
4.00765
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.9814
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.87836
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.85664
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.71249
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.71163
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.66121
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.63358
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.58567
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.33708
|
|
NOTCH1
|
notch 1
|
3.22178
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.18052
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.15034
|
|
CHN1
|
chimerin 1
|
2.68027
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.65039
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.53517
|
|
EPHA3
|
EPH receptor A3
|
2.33097
|
|
JADE2
|
jade family PHD finger 2
|
2.20539
|
|
CSK
|
c-src tyrosine kinase
|
2.11106
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.07386
|
|
E2F2
|
E2F transcription factor 2
|
2.06329
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.00427
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.19224
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.90292
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.75992
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.73112
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.69672
|
|
LDHD
|
lactate dehydrogenase D
|
-3.60729
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.5925
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.52043
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.97482
|
|
THAP11
|
THAP domain containing 11
|
-2.80004
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.59755
|
|
CCNB1
|
cyclin B1
|
-2.58235
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.53306
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.47307
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.46637
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.40643
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.36425
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.2394
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.13017
|
|
EGF
|
epidermal growth factor
|
-2.11582
|
