CRCGN012_HEPG2_24H:B10 Gene Set
Genes
25 genes differentially expressed following the CRCGN012_HEPG2_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
6.28033
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
6.10898
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.07961
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.06924
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.77095
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.06245
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
2.75355
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.6565
|
|
MAP7
|
microtubule-associated protein 7
|
2.60693
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.31907
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.30535
|
|
KIF14
|
kinesin family member 14
|
2.24491
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.23509
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.17015
|
|
GPATCH8
|
G patch domain containing 8
|
2.07122
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.59392
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.06668
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.05908
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-3.07612
|
|
SCAND1
|
SCAN domain containing 1
|
-3.01262
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.85693
|
|
RAI14
|
retinoic acid induced 14
|
-2.12069
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1038
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.05976
|
|
ZNF646
|
zinc finger protein 646
|
-2.05175
|
