CRCGN012_HEPG2_24H:B11 Gene Set
Genes
41 genes differentially expressed following the CRCGN012_HEPG2_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.16494
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.41448
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.65242
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.49842
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.3773
|
|
UBQLN2
|
ubiquilin 2
|
3.22129
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.12249
|
|
EVL
|
Enah/Vasp-like
|
2.98238
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.9384
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.77589
|
|
CSK
|
c-src tyrosine kinase
|
2.69422
|
|
CCNH
|
cyclin H
|
2.60865
|
|
FZD7
|
frizzled class receptor 7
|
2.47934
|
|
PRR15L
|
proline rich 15-like
|
2.41278
|
|
TLR4
|
toll-like receptor 4
|
2.3987
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.39434
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.37979
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.17765
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.45511
|
|
VAT1
|
vesicle amine transport 1
|
-6.42773
|
|
THAP11
|
THAP domain containing 11
|
-6.42152
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.73304
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.62588
|
|
CCNB1
|
cyclin B1
|
-3.50547
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.46707
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.38169
|
|
ZNF586
|
zinc finger protein 586
|
-3.33872
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.33386
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.24738
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.87224
|
|
GNAS
|
GNAS complex locus
|
-2.65886
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.56704
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.54894
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.52847
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.51135
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.39509
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.29575
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.23251
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.22929
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.16286
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.04113
|
