CRCGN012_HEPG2_24H:B13 Gene Set
Genes
52 genes differentially expressed following the CRCGN012_HEPG2_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
7.3695
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.14036
|
|
E2F2
|
E2F transcription factor 2
|
4.35105
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.30983
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.19661
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.08231
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.91325
|
|
RPL39L
|
ribosomal protein L39-like
|
3.80388
|
|
CSK
|
c-src tyrosine kinase
|
3.66982
|
|
UBQLN2
|
ubiquilin 2
|
3.46024
|
|
MOK
|
MOK protein kinase
|
3.43845
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.17532
|
|
CCDC92
|
coiled-coil domain containing 92
|
3.17199
|
|
AXIN1
|
axin 1
|
2.98325
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.89302
|
|
KIF5C
|
kinesin family member 5C
|
2.79651
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.74883
|
|
KHDC4
|
KH domain containing 4, pre-mRNA splicing factor
|
2.60948
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.51053
|
|
JADE2
|
jade family PHD finger 2
|
2.47863
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.41918
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.41065
|
|
TEX10
|
testis expressed 10
|
2.27662
|
|
BLMH
|
bleomycin hydrolase
|
2.24975
|
|
GATA3
|
GATA binding protein 3
|
2.20788
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
2.08097
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.05454
|
|
KIF14
|
kinesin family member 14
|
2.04002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-7.70174
|
|
LDHD
|
lactate dehydrogenase D
|
-6.59338
|
|
HMG20B
|
high mobility group 20B
|
-3.63871
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.59645
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.49876
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.03034
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.9761
|
|
DNM1L
|
dynamin 1-like
|
-2.96714
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.77407
|
|
CCNB2
|
cyclin B2
|
-2.74617
|
|
SNX11
|
sorting nexin 11
|
-2.6301
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.59752
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.52319
|
|
GNAS
|
GNAS complex locus
|
-2.50944
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.5043
|
|
EGF
|
epidermal growth factor
|
-2.50016
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.4922
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.3454
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.32184
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.2694
|
|
RAI14
|
retinoic acid induced 14
|
-2.2629
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.10159
|
|
CD320
|
CD320 molecule
|
-2.09823
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.00596
|
