CRCGN012_HEPG2_24H:B14 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.5618
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.47542
|
|
CSK
|
c-src tyrosine kinase
|
4.35735
|
|
INTS3
|
integrator complex subunit 3
|
4.02023
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.98781
|
|
CHN1
|
chimerin 1
|
3.91673
|
|
JADE2
|
jade family PHD finger 2
|
3.72968
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.32939
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.97975
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.90186
|
|
EPHA3
|
EPH receptor A3
|
2.77424
|
|
CHEK2
|
checkpoint kinase 2
|
2.74929
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.71679
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.65261
|
|
E2F2
|
E2F transcription factor 2
|
2.4759
|
|
EVL
|
Enah/Vasp-like
|
2.44142
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.43937
|
|
PRKCH
|
protein kinase C, eta
|
2.41825
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.34173
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-8.284
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.85826
|
|
DNM1L
|
dynamin 1-like
|
-4.63753
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.36305
|
|
VAT1
|
vesicle amine transport 1
|
-4.1546
|
|
MAP7
|
microtubule-associated protein 7
|
-3.80341
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.30973
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.17227
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.13707
|
|
CCNB1
|
cyclin B1
|
-2.65684
|
|
THAP11
|
THAP domain containing 11
|
-2.63889
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.56872
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.49661
|
|
PLK1
|
polo-like kinase 1
|
-2.48441
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.41677
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.1038
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.05428
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.01393
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.0126
|
