CRCGN012_HEPG2_24H:B15 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
9.61215
|
|
STIMATE
|
STIM activating enhancer
|
5.87591
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.01137
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.39418
|
|
EPHB2
|
EPH receptor B2
|
4.17724
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.67484
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.63309
|
|
EPN2
|
epsin 2
|
3.52359
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.49507
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.37441
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.9364
|
|
MYLK
|
myosin light chain kinase
|
2.74597
|
|
CSK
|
c-src tyrosine kinase
|
2.47726
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.34122
|
|
NMU
|
neuromedin U
|
2.21157
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.17905
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.06438
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.2066
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.38442
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.49018
|
|
NUP93
|
nucleoporin 93kDa
|
-3.9586
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.70338
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.45643
|
|
PEG10
|
paternally expressed 10
|
-3.09061
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.07281
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.85876
|
|
GOLT1B
|
golgi transport 1B
|
-2.80353
|
|
DNM1L
|
dynamin 1-like
|
-2.71009
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.63121
|
|
MAP7
|
microtubule-associated protein 7
|
-2.55585
|
|
GNAS
|
GNAS complex locus
|
-2.52837
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.32171
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.28036
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.26495
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.26254
|
|
USP6NL
|
USP6 N-terminal like
|
-2.22379
|
|
CPNE3
|
copine III
|
-2.17485
|
|
NUDC
|
nudC nuclear distribution protein
|
-2.16764
|
|
LDHD
|
lactate dehydrogenase D
|
-2.06849
|
