CRCGN012_HEPG2_24H:B17 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.80022
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
6.21861
|
|
CHN1
|
chimerin 1
|
4.99538
|
|
MCOLN1
|
mucolipin 1
|
4.37994
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.68877
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
3.60369
|
|
STIMATE
|
STIM activating enhancer
|
3.48866
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.15669
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.05116
|
|
PMM2
|
phosphomannomutase 2
|
2.93974
|
|
KLHL21
|
kelch-like family member 21
|
2.92323
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.91195
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.87183
|
|
E2F2
|
E2F transcription factor 2
|
2.84304
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.74762
|
|
EPHA3
|
EPH receptor A3
|
2.57694
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.54703
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.49226
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.48972
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.439
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.31683
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.13318
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.16173
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.9805
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.88637
|
|
GDF15
|
growth differentiation factor 15
|
-5.48337
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.65846
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.95017
|
|
EGF
|
epidermal growth factor
|
-3.68083
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.37293
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.36684
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.30099
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.25008
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-3.21805
|
|
STX4
|
syntaxin 4
|
-3.20255
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.08309
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.07432
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.86422
|
|
FHL2
|
four and a half LIM domains 2
|
-2.86143
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.77735
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.56605
|
|
GNAS
|
GNAS complex locus
|
-2.48142
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.17727
|
|
CDC25B
|
cell division cycle 25B
|
-2.15745
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.13712
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.13604
|
|
FBXO34
|
F-box protein 34
|
-2.00799
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.00068
|
