| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4'-(chloroacetyl)acetanilide 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
62 genes differentially expressed following the CRCGN012_HEPG2_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.28661 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.9801 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.31494 |
| STIMATE | STIM activating enhancer | 4.90125 |
| ADRB2 | adrenoceptor beta 2, surface | 4.38515 |
| MSRA | methionine sulfoxide reductase A | 4.01225 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.99268 |
| LCN2 | lipocalin 2 | 3.83428 |
| ATP11B | ATPase, class VI, type 11B | 3.58968 |
| STK10 | serine/threonine kinase 10 | 3.32806 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.27736 |
| UBQLN2 | ubiquilin 2 | 3.27234 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.21638 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.16277 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.09836 |
| EPHB2 | EPH receptor B2 | 2.93597 |
| ABHD6 | abhydrolase domain containing 6 | 2.50865 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.45356 |
| CTNNBL1 | catenin, beta like 1 | 2.44065 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.36994 |
| NOSIP | nitric oxide synthase interacting protein | 2.35025 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 2.33413 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.29422 |
| SAA2 | serum amyloid A2 | 2.24545 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.23335 |
| CHN1 | chimerin 1 | 2.22388 |
| TERF2 | telomeric repeat binding factor 2 | 2.2118 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.13745 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.13532 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.05786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -6.11086 |
| CCNB2 | cyclin B2 | -5.67797 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.08076 |
| PLK1 | polo-like kinase 1 | -4.06179 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.94375 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.89282 |
| EGF | epidermal growth factor | -3.78005 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.4423 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.39461 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.39006 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.08346 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.92017 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.91721 |
| TLCD3A | TLC domain containing 3A | -2.88995 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.74631 |
| CHMP4B | charged multivesicular body protein 4B | -2.73737 |
| GDF15 | growth differentiation factor 15 | -2.65335 |
| CCNB1 | cyclin B1 | -2.6222 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.57633 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.49858 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | -2.42745 |
| PEG10 | paternally expressed 10 | -2.40253 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.29612 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.23741 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.17092 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.14448 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.12824 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated | -2.08797 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.08007 |
| CAPNS1 | calpain, small subunit 1 | -2.0726 |
| COG7 | component of oligomeric golgi complex 7 | -2.07181 |
| PRPF4 | pre-mRNA processing factor 4 | -2.03105 |
