CRCGN012_HEPG2_24H:B19 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.82933
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.71679
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.20713
|
|
HOXA10
|
homeobox A10
|
4.13803
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.10438
|
|
UBQLN2
|
ubiquilin 2
|
3.6523
|
|
STIMATE
|
STIM activating enhancer
|
3.42926
|
|
STK10
|
serine/threonine kinase 10
|
3.23877
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.22401
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.0628
|
|
CRTAP
|
cartilage associated protein
|
2.83133
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.806
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.71823
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.62689
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.54876
|
|
VGLL4
|
vestigial-like family member 4
|
2.53942
|
|
KIF14
|
kinesin family member 14
|
2.49982
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.44558
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.438
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.33811
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.2684
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.25938
|
|
TLR4
|
toll-like receptor 4
|
2.23643
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.07559
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.065
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.20069
|
|
LDHD
|
lactate dehydrogenase D
|
-7.04061
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-5.96882
|
|
VAT1
|
vesicle amine transport 1
|
-4.73781
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.52789
|
|
SCAND1
|
SCAN domain containing 1
|
-3.40429
|
|
ZNF586
|
zinc finger protein 586
|
-3.21502
|
|
DSG2
|
desmoglein 2
|
-3.14032
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
-2.94986
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.82398
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.72112
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.66941
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.58096
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.45692
|
|
SNX11
|
sorting nexin 11
|
-2.40952
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.37811
|
|
PGM1
|
phosphoglucomutase 1
|
-2.3716
|
|
TCTN1
|
tectonic family member 1
|
-2.36162
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.29219
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.24181
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.18147
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.13532
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.11048
|
