| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-oxydianiline 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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63 genes differentially expressed following the CRCGN012_HEPG2_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 8.93288 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.49967 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.21193 |
| LCN2 | lipocalin 2 | 5.12143 |
| CHMP6 | charged multivesicular body protein 6 | 4.56358 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 4.53633 |
| TAC4 | tachykinin 4 (hemokinin) | 4.46559 |
| E2F2 | E2F transcription factor 2 | 4.35361 |
| CSK | c-src tyrosine kinase | 4.27626 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.21724 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.16671 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.6466 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.23375 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.17677 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.14448 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.03564 |
| CEP57 | centrosomal protein 57kDa | 3.0267 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.01777 |
| KIF14 | kinesin family member 14 | 2.87263 |
| LOC122526780 | uncharacterized LOC122526780 | 2.64117 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.59098 |
| ATP11B | ATPase, class VI, type 11B | 2.56228 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.53688 |
| HYOU1 | hypoxia up-regulated 1 | 2.53274 |
| TXNL4B | thioredoxin-like 4B | 2.3406 |
| GATA3 | GATA binding protein 3 | 2.31353 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.30213 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 2.28941 |
| SLAMF7 | SLAM family member 7 | 2.28419 |
| CCNH | cyclin H | 2.26568 |
| MEST | mesoderm specific transcript | 2.21495 |
| TBP | TATA box binding protein | 2.05941 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.02061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -6.55391 |
| NUP93 | nucleoporin 93kDa | -5.65699 |
| CD320 | CD320 molecule | -5.5839 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.5142 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.07965 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -4.69333 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.54584 |
| COG2 | component of oligomeric golgi complex 2 | -4.1715 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.11307 |
| SLC35F2 | solute carrier family 35, member F2 | -4.07978 |
| ISOC1 | isochorismatase domain containing 1 | -4.07217 |
| RPS5 | ribosomal protein S5 | -3.63524 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.56084 |
| GDF15 | growth differentiation factor 15 | -3.46419 |
| CCNB2 | cyclin B2 | -3.3581 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.26738 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.10296 |
| PEG10 | paternally expressed 10 | -2.92204 |
| SNX11 | sorting nexin 11 | -2.80378 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.68937 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.68012 |
| CCNB1 | cyclin B1 | -2.61917 |
| TRIM24 | tripartite motif containing 24 | -2.21555 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.18956 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.1828 |
| RAB23 | RAB23, member RAS oncogene family | -2.12016 |
| FXYD7 | FXYD domain containing ion transport regulator 7 | -2.09248 |
| RPL34 | ribosomal protein L34 | -2.06959 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.05202 |
| HMOX1 | heme oxygenase 1 | -2.02673 |