CRCGN012_HEPG2_24H:B21 Gene Set
Genes
37 genes differentially expressed following the CRCGN012_HEPG2_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.49732
|
|
E2F2
|
E2F transcription factor 2
|
7.34457
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
7.23723
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
6.96363
|
|
GPATCH8
|
G patch domain containing 8
|
4.20264
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.91021
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.48928
|
|
CSK
|
c-src tyrosine kinase
|
3.29404
|
|
STIMATE
|
STIM activating enhancer
|
3.10789
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.92978
|
|
HOXA10
|
homeobox A10
|
2.84476
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.83226
|
|
LAGE3
|
L antigen family, member 3
|
2.76145
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.70583
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.56713
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.53547
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.52477
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.22665
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.20196
|
|
MMP1
|
matrix metallopeptidase 1
|
2.19188
|
|
PFKL
|
phosphofructokinase, liver
|
2.18434
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.10724
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.97604
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.28168
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.19629
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.88458
|
|
LDHD
|
lactate dehydrogenase D
|
-4.57083
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-3.53619
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.42534
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.87039
|
|
EGF
|
epidermal growth factor
|
-2.81821
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.33768
|
|
CCNB2
|
cyclin B2
|
-2.30465
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1989
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.14846
|
|
HMG20B
|
high mobility group 20B
|
-2.1258
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.06341
|
