CRCGN012_HEPG2_24H:B22 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.09957
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
5.06161
|
|
LCN2
|
lipocalin 2
|
4.91841
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.33376
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
4.14267
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.7008
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.65966
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.20028
|
|
CCNF
|
cyclin F
|
3.18422
|
|
CCDC92
|
coiled-coil domain containing 92
|
3.15588
|
|
CYCS
|
cytochrome c, somatic
|
3.1116
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.00877
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.92849
|
|
CHN1
|
chimerin 1
|
2.80721
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.74458
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.72403
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.47307
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.35918
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.35107
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.31621
|
|
NEDD4
|
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
|
2.12003
|
|
CEP57
|
centrosomal protein 57kDa
|
2.10494
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
2.04595
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.00419
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.1236
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.9045
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.87858
|
|
NISCH
|
nischarin
|
-3.60772
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.52302
|
|
LDHD
|
lactate dehydrogenase D
|
-3.2575
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.04089
|
|
HMG20B
|
high mobility group 20B
|
-2.66663
|
|
CCNB1
|
cyclin B1
|
-2.56234
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.53124
|
|
PFKFB3
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
|
-2.32884
|
|
BPGM
|
2,3-bisphosphoglycerate mutase
|
-2.22025
|
|
GOLT1B
|
golgi transport 1B
|
-2.14099
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.08527
|
|
STON1
|
stonin 1
|
-2.02447
|
