CRCGN012_HEPG2_24H:B24 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.21318
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
6.19604
|
|
CYCS
|
cytochrome c, somatic
|
3.81772
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.78835
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.60869
|
|
MYLK
|
myosin light chain kinase
|
3.52769
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.50564
|
|
CBR3
|
carbonyl reductase 3
|
3.36453
|
|
E2F2
|
E2F transcription factor 2
|
3.30563
|
|
CSK
|
c-src tyrosine kinase
|
3.2734
|
|
MOK
|
MOK protein kinase
|
3.18256
|
|
STIMATE
|
STIM activating enhancer
|
3.17109
|
|
CHN1
|
chimerin 1
|
3.1602
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.04139
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.80256
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.76132
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.59683
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.38121
|
|
PRR15L
|
proline rich 15-like
|
2.24747
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.02366
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.01837
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.01406
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-6.69736
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.78698
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-3.78329
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.7069
|
|
DSG2
|
desmoglein 2
|
-3.66253
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.43241
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.42236
|
|
GOLT1B
|
golgi transport 1B
|
-3.30214
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.28567
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.23619
|
|
CD58
|
CD58 molecule
|
-2.75097
|
|
EGF
|
epidermal growth factor
|
-2.34132
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.33019
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.29946
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.26168
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.21614
|
