CRCGN012_HEPG2_24H:C03 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.30185
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.2801
|
|
CSK
|
c-src tyrosine kinase
|
4.06865
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.29787
|
|
E2F2
|
E2F transcription factor 2
|
3.24323
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.21829
|
|
CHN1
|
chimerin 1
|
3.19987
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.12506
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.99939
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.95647
|
|
JADE2
|
jade family PHD finger 2
|
2.85777
|
|
EPHA3
|
EPH receptor A3
|
2.81425
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.42594
|
|
PRKCH
|
protein kinase C, eta
|
2.27504
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.17818
|
|
TLR4
|
toll-like receptor 4
|
2.17116
|
|
INTS3
|
integrator complex subunit 3
|
2.12179
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.05651
|
|
NMU
|
neuromedin U
|
2.04363
|
|
KIF14
|
kinesin family member 14
|
2.03863
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.73683
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.76256
|
|
GDF15
|
growth differentiation factor 15
|
-4.5801
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.35773
|
|
EGF
|
epidermal growth factor
|
-4.22914
|
|
CCNB2
|
cyclin B2
|
-4.04812
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.97322
|
|
MAP7
|
microtubule-associated protein 7
|
-3.72434
|
|
WASHC4
|
WASH complex subunit 4
|
-3.69883
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.17834
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.04848
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.85854
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.84654
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.74407
|
|
MVP
|
major vault protein
|
-2.71473
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.57246
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.47078
|
|
NID2
|
nidogen 2 (osteonidogen)
|
-2.34165
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.32421
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.21117
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.16052
|
|
NAT10
|
N-acetyltransferase 10 (GCN5-related)
|
-2.1335
|
|
CD58
|
CD58 molecule
|
-2.02953
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.02752
|