CRCGN012_HEPG2_24H:C03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description eugenol 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN012_HEPG2_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.30185
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.2801
CSK c-src tyrosine kinase 4.06865
NOSIP nitric oxide synthase interacting protein 3.29787
E2F2 E2F transcription factor 2 3.24323
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.21829
CHN1 chimerin 1 3.19987
CHMP6 charged multivesicular body protein 6 3.12506
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.99939
GPER1 G protein-coupled estrogen receptor 1 2.95647
JADE2 jade family PHD finger 2 2.85777
EPHA3 EPH receptor A3 2.81425
CIAO3 cytosolic iron-sulfur assembly component 3 2.42594
PRKCH protein kinase C, eta 2.27504
ABHD6 abhydrolase domain containing 6 2.17818
TLR4 toll-like receptor 4 2.17116
INTS3 integrator complex subunit 3 2.12179
PPARG peroxisome proliferator-activated receptor gamma 2.05651
NMU neuromedin U 2.04363
KIF14 kinesin family member 14 2.03863

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.73683
MAPK13 mitogen-activated protein kinase 13 -5.76256
GDF15 growth differentiation factor 15 -4.5801
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.35773
EGF epidermal growth factor -4.22914
CCNB2 cyclin B2 -4.04812
KDM3A lysine (K)-specific demethylase 3A -3.97322
MAP7 microtubule-associated protein 7 -3.72434
WASHC4 WASH complex subunit 4 -3.69883
CHMP4B charged multivesicular body protein 4B -3.17834
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.04848
MRPS2 mitochondrial ribosomal protein S2 -2.85854
PDHX pyruvate dehydrogenase complex, component X -2.84654
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.74407
MVP major vault protein -2.71473
SSBP2 single-stranded DNA binding protein 2 -2.57246
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.47078
NID2 nidogen 2 (osteonidogen) -2.34165
LOC124907782 dual specificity protein phosphatase 22 -2.32421
FGFR4 fibroblast growth factor receptor 4 -2.21117
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.16052
NAT10 N-acetyltransferase 10 (GCN5-related) -2.1335
CD58 CD58 molecule -2.02953
HLA-DMA major histocompatibility complex, class II, DM alpha -2.02752