CRCGN012_HEPG2_24H:C04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description eugenol 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN012_HEPG2_24H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 3.3445
CSK c-src tyrosine kinase 3.34063
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.20138
CDK6 cyclin-dependent kinase 6 2.85715
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.68783
RPL39L ribosomal protein L39-like 2.57574
STXBP2 syntaxin binding protein 2 2.55345
ABHD6 abhydrolase domain containing 6 2.5449
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.5221
AXIN1 axin 1 2.36716
GARRE1 granule associated Rac and RHOG effector 1 2.28944
ECD ecdysoneless homolog (Drosophila) 2.13355
PCNA proliferating cell nuclear antigen 2.09101

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.57992
CDC20 cell division cycle 20 -3.44062
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.27256
COG2 component of oligomeric golgi complex 2 -3.03984
MRPS2 mitochondrial ribosomal protein S2 -2.47999
PDLIM1 PDZ and LIM domain 1 -2.41066
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.32621
FGFR4 fibroblast growth factor receptor 4 -2.28333
NRIP1 nuclear receptor interacting protein 1 -2.26265
RGS2 regulator of G-protein signaling 2 -2.20878
SLC35F2 solute carrier family 35, member F2 -2.15486
GNAS GNAS complex locus -2.03952