| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | eugenol 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN012_HEPG2_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.61908 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.92411 |
| CHMP6 | charged multivesicular body protein 6 | 4.6869 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.6058 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.32908 |
| GATA3 | GATA binding protein 3 | 3.99528 |
| CHN1 | chimerin 1 | 3.97117 |
| ABHD4 | abhydrolase domain containing 4 | 3.88677 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.67975 |
| PRKCH | protein kinase C, eta | 3.61799 |
| CSK | c-src tyrosine kinase | 3.43432 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.02471 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.88033 |
| LCN2 | lipocalin 2 | 2.6909 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.36509 |
| PCNA | proliferating cell nuclear antigen | 2.31108 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.2619 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.23969 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.16194 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 2.14566 |
| TASP1 | taspase, threonine aspartase, 1 | 2.13992 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.11644 |
| JADE2 | jade family PHD finger 2 | 2.08507 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 2.08013 |
| TEX10 | testis expressed 10 | 2.07773 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 2.04599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -7.84345 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.63918 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.64143 |
| ADI1 | acireductone dioxygenase 1 | -5.49385 |
| CCNB2 | cyclin B2 | -4.50294 |
| ZNF586 | zinc finger protein 586 | -4.3849 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.37576 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.23061 |
| TMEM109 | transmembrane protein 109 | -4.1066 |
| TUBB6 | tubulin, beta 6 class V | -4.09037 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.35234 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.27014 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.10084 |
| RNF167 | ring finger protein 167 | -3.01783 |
| TLCD3A | TLC domain containing 3A | -2.87007 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.74894 |
| TMEM115 | transmembrane protein 115 | -2.60352 |
| UBXN6 | UBX domain protein 6 | -2.40487 |
| IFRD2 | interferon-related developmental regulator 2 | -2.38306 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.3201 |
| ADIPOR1 | adiponectin receptor 1 | -2.26966 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -2.25231 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.20233 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -2.14992 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -2.14991 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -2.10558 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 | -2.07278 |
| GJB1 | gap junction protein, beta 1, 32kDa | -2.05465 |
| MST1R | macrophage stimulating 1 receptor | -2.04244 |
| REEP5 | receptor accessory protein 5 | -2.03101 |
| PDIA2 | protein disulfide isomerase family A, member 2 | -2.0117 |
| ATG9A | autophagy related 9A | -2.00223 |
