| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pentachlorophenol 4.92 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN012_HEPG2_24H:C10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 3.95513 |
| MYLK | myosin light chain kinase | 3.91645 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.779 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.68639 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.67732 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.65682 |
| LOC122526780 | uncharacterized LOC122526780 | 3.62792 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.5681 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.39451 |
| LCN2 | lipocalin 2 | 3.31285 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.30621 |
| CDC45 | cell division cycle 45 | 3.165 |
| NOSIP | nitric oxide synthase interacting protein | 3.02399 |
| CBR3 | carbonyl reductase 3 | 2.92484 |
| TXNRD1 | thioredoxin reductase 1 | 2.86766 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.7718 |
| AXIN1 | axin 1 | 2.75495 |
| PMM2 | phosphomannomutase 2 | 2.66757 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.56841 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.49819 |
| ATP11B | ATPase, class VI, type 11B | 2.49435 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.42846 |
| STXBP2 | syntaxin binding protein 2 | 2.19874 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.12155 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.00028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.50005 |
| CCNB2 | cyclin B2 | -5.52177 |
| TRIB3 | tribbles pseudokinase 3 | -5.09495 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -4.06802 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.95379 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.75631 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.61904 |
| TRAPPC3 | trafficking protein particle complex 3 | -3.5722 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.54286 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.47624 |
| CHMP4B | charged multivesicular body protein 4B | -3.40993 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.18358 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.1417 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.95756 |
| CDC20 | cell division cycle 20 | -2.94993 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.94216 |
| TOR1A | torsin family 1, member A (torsin A) | -2.83829 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.80142 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.79814 |
| GDF15 | growth differentiation factor 15 | -2.76696 |
| ADI1 | acireductone dioxygenase 1 | -2.6786 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.58043 |
| LDHD | lactate dehydrogenase D | -2.53728 |
| SLC35F2 | solute carrier family 35, member F2 | -2.38937 |
| COG2 | component of oligomeric golgi complex 2 | -2.18236 |
| GNAS | GNAS complex locus | -2.17706 |
| ZNF586 | zinc finger protein 586 | -2.08925 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.00832 |
