CRCGN012_HEPG2_24H:C11 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:C11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.91253
|
|
CSK
|
c-src tyrosine kinase
|
6.36748
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.33281
|
|
CYCS
|
cytochrome c, somatic
|
4.11734
|
|
PRR15L
|
proline rich 15-like
|
4.11121
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.62957
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.52605
|
|
MCOLN1
|
mucolipin 1
|
3.33887
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.16735
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.08903
|
|
UBQLN2
|
ubiquilin 2
|
3.01517
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.84984
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.77265
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.66987
|
|
TEX10
|
testis expressed 10
|
2.38301
|
|
STIMATE
|
STIM activating enhancer
|
2.38189
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.35514
|
|
GATA3
|
GATA binding protein 3
|
2.19909
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.15765
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.14504
|
|
VAT1
|
vesicle amine transport 1
|
2.02398
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.46661
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.33776
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.32056
|
|
LDHD
|
lactate dehydrogenase D
|
-3.16812
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.12605
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.02729
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.0246
|
|
ARFIP2
|
ADP-ribosylation factor interacting protein 2
|
-2.90858
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.78033
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.65233
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.61245
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.49801
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.46425
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.34624
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.32175
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.28898
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.21262
|
|
LCN1
|
lipocalin 1
|
-2.13081
|
