| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pentachlorophenol 1.23 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN012_HEPG2_24H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 7.36985 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.94636 |
| HOXA10 | homeobox A10 | 5.76511 |
| CHN1 | chimerin 1 | 4.87172 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.83676 |
| DENND2D | DENN/MADD domain containing 2D | 4.35988 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.32262 |
| PLSCR1 | phospholipid scramblase 1 | 3.93623 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.66836 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.2235 |
| MYLK | myosin light chain kinase | 3.03732 |
| NOSIP | nitric oxide synthase interacting protein | 2.81357 |
| UBQLN2 | ubiquilin 2 | 2.7855 |
| LCN2 | lipocalin 2 | 2.73665 |
| CYCS | cytochrome c, somatic | 2.62696 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.53354 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.52496 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.38208 |
| IFI44L | interferon-induced protein 44-like | 2.28775 |
| HDGFL3 | HDGF like 3 | 2.24873 |
| SLC75A1 | solute carrier family 75 member 1 | 2.23364 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.20045 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.1548 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.11638 |
| MX1 | MX dynamin-like GTPase 1 | 2.10208 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.01496 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.41127 |
| LDHD | lactate dehydrogenase D | -4.63781 |
| CCNB2 | cyclin B2 | -4.54467 |
| GNAS | GNAS complex locus | -4.46744 |
| SLC35F2 | solute carrier family 35, member F2 | -3.04014 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | -3.00961 |
| IFRD2 | interferon-related developmental regulator 2 | -2.97197 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.85757 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.74069 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.50763 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.49712 |
| ADI1 | acireductone dioxygenase 1 | -2.473 |
| RNF25 | ring finger protein 25 | -2.378 |
| MTA2 | metastasis associated 1 family, member 2 | -2.28911 |
| HSPA4 | heat shock 70kDa protein 4 | -2.26875 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.25369 |
| NVL | nuclear VCP-like | -2.24574 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.24527 |
| SNX11 | sorting nexin 11 | -2.24189 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.23063 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.20681 |
| FBXL8 | F-box and leucine-rich repeat protein 8 | -2.11601 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) | -2.09306 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -2.07732 |
| TRAIP | TRAF interacting protein | -2.04723 |
| LYPD1 | LY6/PLAUR domain containing 1 | -2.02494 |
| USP19 | ubiquitin specific peptidase 19 | -2.02457 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.02434 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.00737 |
