CRCGN012_HEPG2_24H:C19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1029 genes differentially expressed following the CRCGN012_HEPG2_24H:C19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MCOLN1 mucolipin 1 7.755
TESK1 testis-specific kinase 1 7.5508
HEBP1 heme binding protein 1 7.43852
ADGRE5 adhesion G protein-coupled receptor E5 7.2881
BACE2 beta-site APP-cleaving enzyme 2 7.0983
STIMATE STIM activating enhancer 6.8572
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 6.6256
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 6.59067
PPP1R13B protein phosphatase 1, regulatory subunit 13B 6.54495
UBE2L6 ubiquitin-conjugating enzyme E2L 6 6.35514
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 6.21371
MEST mesoderm specific transcript 6.10727
TIMP2 TIMP metallopeptidase inhibitor 2 5.94254
MSRA methionine sulfoxide reductase A 5.85829
TENT4A terminal nucleotidyltransferase 4A 5.80801
PNKP polynucleotide kinase 3'-phosphatase 5.79992
TMEM109 transmembrane protein 109 5.75346
CIAO3 cytosolic iron-sulfur assembly component 3 5.72272
SHB Src homology 2 domain containing adaptor protein B 5.13247
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 5.03698
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 5.02543
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.87035
PFKL phosphofructokinase, liver 4.84894
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.79706
CAPN1 calpain 1, (mu/I) large subunit 4.72252
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 4.65831
FCHO1 FCH domain only 1 4.65376
HTRA1 HtrA serine peptidase 1 4.59438
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 4.56193
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 4.55314
SOCS2 suppressor of cytokine signaling 2 4.46439
IL1B interleukin 1, beta 4.44007
TRAPPC6A trafficking protein particle complex 6A 4.30674
PTK2B protein tyrosine kinase 2 beta 4.17473
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 4.15377
SMIM40 small integral membrane protein 40 4.14881
ISOC1 isochorismatase domain containing 1 4.12921
NVL nuclear VCP-like 4.12126
SIPA1L3 signal-induced proliferation-associated 1 like 3 4.11195
DPH2 DPH2 homolog (S. cerevisiae) 4.10713
EXD3 exonuclease 3'-5' domain containing 3 4.05013
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 4.03829
GFOD1 glucose-fructose oxidoreductase domain containing 1 4.03164
NOTCH1 notch 1 3.99743
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.95691
C2CD2 C2 calcium-dependent domain containing 2 3.93409
TCEA2 transcription elongation factor A (SII), 2 3.8969
H2BC21 H2B clustered histone 21 3.89159
TERT telomerase reverse transcriptase 3.8844
DYNLT3 dynein, light chain, Tctex-type 3 3.82708
MYL9 myosin, light chain 9, regulatory 3.80929
CD200R1 CD200 receptor 1 3.78704
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.77105
GPC1 glypican 1 3.75485
HPCAL1 hippocalcin-like 1 3.75422
CTSD cathepsin D 3.73714
FZD1 frizzled class receptor 1 3.72106
LCN2 lipocalin 2 3.71751
CCDC85B coiled-coil domain containing 85B 3.70735
MTFR1 mitochondrial fission regulator 1 3.69732
GHR growth hormone receptor 3.69406
BAD BCL2-associated agonist of cell death 3.67897
LYN LYN proto-oncogene, Src family tyrosine kinase 3.67689
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 3.58824
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 3.58049
IFT54 intraflagellar transport 54 3.57352
GSTZ1 glutathione S-transferase zeta 1 3.52729
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine 3.51378
STXBP2 syntaxin binding protein 2 3.47367
FGFR2 fibroblast growth factor receptor 2 3.4664
PTP4A3 protein tyrosine phosphatase type IVA, member 3 3.46334
CBR3 carbonyl reductase 3 3.45065
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.4484
FAM246A family with sequence similarity 246 member A 3.4361
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.43594
IPO13 importin 13 3.42279
PRR15L proline rich 15-like 3.41575
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.41321
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 3.41
COL4A1 collagen, type IV, alpha 1 3.38221
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.38006
PTMS parathymosin 3.37771
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 3.37722
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 3.37674
VAC14 Vac14 homolog (S. cerevisiae) 3.33087
ANO1 anoctamin 1, calcium activated chloride channel 3.31358
FAIM Fas apoptotic inhibitory molecule 3.31065
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.29747
ITFG1 integrin alpha FG-GAP repeat containing 1 3.27689
NUCB1 nucleobindin 1 3.24292
ECH1 enoyl CoA hydratase 1, peroxisomal 3.24201
TSC22D3 TSC22 domain family, member 3 3.24075
GATD3 glutamine amidotransferase class 1 domain containing 3 3.23633
ERI3 ERI1 exoribonuclease family member 3 3.22197
SH3D19 SH3 domain containing 19 3.22184
DGCR6L DiGeorge syndrome critical region gene 6-like 3.21356
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 3.20101
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 3.18924
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.1848
LAGE3 L antigen family, member 3 3.17528
PCLO piccolo presynaptic cytomatrix protein 3.17448
HUNK hormonally up-regulated Neu-associated kinase 3.17132
MEGF6 multiple EGF-like-domains 6 3.16495
FLT4 fms-related tyrosine kinase 4 3.16458
PRKX protein kinase, X-linked 3.14588
MYO1D myosin ID 3.14581
ARL4C ADP-ribosylation factor-like 4C 3.1426
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 3.13848
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.13392
PLCH2 phospholipase C, eta 2 3.12276
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 3.1042
PTPRK protein tyrosine phosphatase, receptor type, K 3.0962
RNLS renalase, FAD-dependent amine oxidase 3.09574
GADD45A growth arrest and DNA-damage-inducible, alpha 3.05643
TMEM156 transmembrane protein 156 3.0533
RBKS ribokinase 3.0509
UBTD1 ubiquitin domain containing 1 3.04785
CLIC5 chloride intracellular channel 5 3.04272
ZNF205 zinc finger protein 205 3.03442
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.03163
UNC13A unc-13 homolog A (C. elegans) 3.02786
TP53 tumor protein p53 3.02382
TOMM34 translocase of outer mitochondrial membrane 34 3.02073
ARHGAP8 Rho GTPase activating protein 8 3.02029
ATP11B ATPase, class VI, type 11B 3.02017
BIRC7 baculoviral IAP repeat containing 7 3.01586
RTL10 retrotransposon Gag like 10 3.00754
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 3.00266
LSR lipolysis stimulated lipoprotein receptor 2.99229
H1-10 H1.10 linker histone 2.9876
ANGPTL2 angiopoietin-like 2 2.98247
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.98228
WASHC5 WASH complex subunit 5 2.98013
PPDPF pancreatic progenitor cell differentiation and proliferation factor 2.97867
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.97589
NEU2 sialidase 2 (cytosolic sialidase) 2.97414
SQOR sulfide quinone oxidoreductase 2.9698
CEMP1 cementum protein 1 2.96905
TEX2 testis expressed 2 2.96333
ADGRG1 adhesion G protein-coupled receptor G1 2.96185
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.96006
RSU1 Ras suppressor protein 1 2.95463
ABHD4 abhydrolase domain containing 4 2.94999
GAS6 growth arrest-specific 6 2.94742
SFXN3 sideroflexin 3 2.9416
THOC6 THO complex 6 2.93375
WDTC1 WD and tetratricopeptide repeats 1 2.93269
ZNF768 zinc finger protein 768 2.92831
SAMD14 sterile alpha motif domain containing 14 2.92231
LPAR3 lysophosphatidic acid receptor 3 2.91906
SEPTIN5 septin 5 2.91865
ACTL8 actin-like 8 2.90911
PALM paralemmin 2.90666
CCL2 chemokine (C-C motif) ligand 2 2.90514
MMP24OS MMP24 opposite strand 2.90474
TDRD3 tudor domain containing 3 2.90208
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.90072
CDK18 cyclin-dependent kinase 18 2.89957
GRB7 growth factor receptor-bound protein 7 2.89454
MMP2 matrix metallopeptidase 2 2.89166
TBC1D31 TBC1 domain family, member 31 2.88877
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.88196
ARMCX4 armadillo repeat containing, X-linked 4 2.88131
SPAG8 sperm associated antigen 8 2.86827
SPTBN2 spectrin, beta, non-erythrocytic 2 2.8628
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.86144
CDC45 cell division cycle 45 2.8593
TRAPPC9 trafficking protein particle complex 9 2.84712
GNL1 guanine nucleotide binding protein-like 1 2.84439
OXCT1 3-oxoacid CoA transferase 1 2.82842
IGFBP3 insulin-like growth factor binding protein 3 2.82737
MTERF3 mitochondrial transcription termination factor 3 2.82545
SYP synaptophysin 2.80861
EML2 echinoderm microtubule associated protein like 2 2.80731
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.79908
HSPB1 heat shock 27kDa protein 1 2.79719
FABP3 fatty acid binding protein 3, muscle and heart 2.79591
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.79386
LPAR2 lysophosphatidic acid receptor 2 2.79285
CXCL2 chemokine (C-X-C motif) ligand 2 2.79249
ZNF358 zinc finger protein 358 2.78919
HSFX2 heat shock transcription factor family, X linked 2 2.78589
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.78564
MAGEA11 melanoma antigen family A11 2.78504
FBXW4 F-box and WD repeat domain containing 4 2.78316
TRADD TNFRSF1A-associated via death domain 2.78063
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.78004
CSK c-src tyrosine kinase 2.7713
VEGFB vascular endothelial growth factor B 2.76777
IKZF4 IKAROS family zinc finger 4 (Eos) 2.76765
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.76694
SYNPO synaptopodin 2.76323
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.7632
TMEM214 transmembrane protein 214 2.7604
KANK3 KN motif and ankyrin repeat domains 3 2.75928
ATG2A autophagy related 2A 2.75721
RUSF1 RUS family member 1 2.75336
CCDC106 coiled-coil domain containing 106 2.74426
H1-2 H1.2 linker histone, cluster member 2.74212
FOXM1 forkhead box M1 2.7407
PRDM9 PR domain containing 9 2.7391
JAG2 jagged 2 2.73705
NUCB2 nucleobindin 2 2.73452
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 2.73184
GRIK4 glutamate receptor, ionotropic, kainate 4 2.72694
HTATSF1 HIV-1 Tat specific factor 1 2.72456
INA internexin neuronal intermediate filament protein, alpha 2.72365
STAP2 signal transducing adaptor family member 2 2.72029
CREG1 cellular repressor of E1A-stimulated genes 1 2.71813
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.70002
RIDA reactive intermediate imine deaminase A homolog 2.69755
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.69722
PSME3IP1 proteasome activator subunit 3 interacting protein 1 2.69652
CKMT1A creatine kinase, mitochondrial 1A 2.68969
WDR62 WD repeat domain 62 2.68854
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.68767
S100G S100 calcium binding protein G 2.68668
FAM234B family with sequence similarity 234 member B 2.68579
ADI1 acireductone dioxygenase 1 2.68207
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.68186
TRAPPC14 trafficking protein particle complex subunit 14 2.67928
AJAP1 adherens junctions associated protein 1 2.67434
GPR32 G protein-coupled receptor 32 2.67113
AMDHD2 amidohydrolase domain containing 2 2.66784
RTL8A retrotransposon Gag like 8A 2.66331
BAX BCL2-associated X protein 2.66251
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 2.66096
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.66066
STX4 syntaxin 4 2.65599
MECR mitochondrial trans-2-enoyl-CoA reductase 2.65588
TOP6BL TOP6B like initiator of meiotic double strand breaks 2.65571
VRTN vertebrae development associated 2.6533
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.6508
FOCAD focadhesin 2.64732
CLEC5A C-type lectin domain family 5, member A 2.6466
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.64599
EPN3 epsin 3 2.64566
CPTP ceramide-1-phosphate transfer protein 2.63877
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.63839
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.6366
MPC2 mitochondrial pyruvate carrier 2 2.63153
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.6268
KL klotho 2.6253
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.6221
POLH polymerase (DNA directed), eta 2.62179
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.61484
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.61364
GRHL2 grainyhead-like 2 (Drosophila) 2.61308
ZNF155 zinc finger protein 155 2.6124
CPLX3 complexin 3 2.60942
IFT57 intraflagellar transport 57 2.60355
HRAS Harvey rat sarcoma viral oncogene homolog 2.60173
PLS3 plastin 3 2.59812
ADRA2C adrenoceptor alpha 2C 2.5894
TMEM40 transmembrane protein 40 2.58916
SCT secretin 2.58762
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.58054
NPAS1 neuronal PAS domain protein 1 2.56972
KIAA0930 KIAA0930 2.5692
RNF44 ring finger protein 44 2.56851
EML3 echinoderm microtubule associated protein like 3 2.56713
INTS8 integrator complex subunit 8 2.55587
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.55579
KRT3 keratin 3, type II 2.55368
GDI1 GDP dissociation inhibitor 1 2.55204
PGLYRP1 peptidoglycan recognition protein 1 2.55159
ISYNA1 inositol-3-phosphate synthase 1 2.55149
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.5407
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.5397
DCTN1 dynactin 1 2.53828
CCNH cyclin H 2.53772
TBXA2R thromboxane A2 receptor 2.53748
PARG poly (ADP-ribose) glycohydrolase 2.53635
IMPG2 interphotoreceptor matrix proteoglycan 2 2.53507
ST18 suppression of tumorigenicity 18, zinc finger 2.52845
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.52538
TMEM63A transmembrane protein 63A 2.52409
HAO2 hydroxyacid oxidase 2 (long chain) 2.52224
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.52157
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.51794
RIN1 Ras and Rab interactor 1 2.5157
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.51447
TRIM11 tripartite motif containing 11 2.51218
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.51197
TBX1 T-box 1 2.51145
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.50338
MYH15 myosin, heavy chain 15 2.49966
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.49924
CRMP1 collapsin response mediator protein 1 2.49591
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.49475
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.49309
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.48904
FGD1 FYVE, RhoGEF and PH domain containing 1 2.48782
RAI14 retinoic acid induced 14 2.4802
HMGA1 high mobility group AT-hook 1 2.47983
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 2.47231
OTUD7B OTU deubiquitinase 7B 2.46545
AURKB aurora kinase B 2.46316
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 2.46216
SOX18 SRY (sex determining region Y)-box 18 2.45642
PDCL3 phosducin-like 3 2.45584
ARL2 ADP-ribosylation factor-like 2 2.45548
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.45522
CBLN1 cerebellin 1 precursor 2.45408
CDK4 cyclin-dependent kinase 4 2.44921
GRAPL GRB2-related adaptor protein-like 2.449
DPY19L4 dpy-19-like 4 (C. elegans) 2.44725
ELMO3 engulfment and cell motility 3 2.44689
FKBP4 FK506 binding protein 4, 59kDa 2.44634
GJA8 gap junction protein, alpha 8, 50kDa 2.44569
ACO1 aconitase 1, soluble 2.44417
SDC1 syndecan 1 2.44192
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 2.43778
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.43671
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.4352
WDR25 WD repeat domain 25 2.43471
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.43357
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.43351
POM121 POM121 transmembrane nucleoporin 2.42883
MAMLD1 mastermind-like domain containing 1 2.4279
FGF5 fibroblast growth factor 5 2.42688
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.42685
ESM1 endothelial cell-specific molecule 1 2.42667
PRTN3 proteinase 3 2.42609
GIPC1 GIPC PDZ domain containing family, member 1 2.4258
C5AR2 complement component 5a receptor 2 2.42347
ESRP1 epithelial splicing regulatory protein 1 2.42117
PECAM1 platelet/endothelial cell adhesion molecule 1 2.41883
PERP PERP, TP53 apoptosis effector 2.41733
H2AJ H2A.J histone 2.41342
VSX1 visual system homeobox 1 2.41244
GBX2 gastrulation brain homeobox 2 2.41194
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 2.41107
TMEM212 transmembrane protein 212 2.41063
HOXB3 homeobox B3 2.40676
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.40594
ESRP2 epithelial splicing regulatory protein 2 2.40131
BHMT2 betaine--homocysteine S-methyltransferase 2 2.40116
IFT38 intraflagellar transport 38 2.39913
DPYSL3 dihydropyrimidinase-like 3 2.39364
FAM204A family with sequence similarity 204, member A 2.39036
TEX13A testis expressed 13A 2.38987
TMPRSS3 transmembrane protease, serine 3 2.38853
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.38818
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.38617
TRO trophinin 2.38309
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.37803
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.37726
MORN1 MORN repeat containing 1 2.37719
GPR45 G protein-coupled receptor 45 2.37334
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 2.3733
THAP4 THAP domain containing 4 2.37297
LDOC1 leucine zipper, down-regulated in cancer 1 2.3723
ADRA2B adrenoceptor alpha 2B 2.37177
ZNF219 zinc finger protein 219 2.36871
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.36523
NMBR neuromedin B receptor 2.36451
KCNK10 potassium channel, two pore domain subfamily K, member 10 2.36363
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.35842
ZNF514 zinc finger protein 514 2.35575
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.35491
EHD2 EH-domain containing 2 2.3519
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.3518
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 2.35134
VAMP7 vesicle-associated membrane protein 7 2.34958
DMTF1 cyclin D binding myb-like transcription factor 1 2.34808
PPP4C protein phosphatase 4, catalytic subunit 2.34734
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.34455
CAV1 caveolin 1, caveolae protein, 22kDa 2.33901
PRKCI protein kinase C, iota 2.33704
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.33672
CXCR4 chemokine (C-X-C motif) receptor 4 2.33606
HPSE heparanase 2.3352
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.33499
RGPD1 RANBP2-like and GRIP domain containing 1 2.33103
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.32914
BTC betacellulin 2.32891
ARMCX2 armadillo repeat containing, X-linked 2 2.32855
GDAP2 ganglioside induced differentiation associated protein 2 2.32824
PSG4 pregnancy specific beta-1-glycoprotein 4 2.32751
RAB43 RAB43, member RAS oncogene family 2.32238
NBAS neuroblastoma amplified sequence 2.32163
PEDS1 plasmanylethanolamine desaturase 1 2.3216
FANCG Fanconi anemia, complementation group G 2.32052
ARRB2 arrestin, beta 2 2.31976
RIPK4 receptor-interacting serine-threonine kinase 4 2.31914
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 2.31788
ZNF385D zinc finger protein 385D 2.31682
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.31325
WDR7 WD repeat domain 7 2.30927
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.3001
CORO1A coronin, actin binding protein, 1A 2.2967
MMRN2 multimerin 2 2.29648
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.29563
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.29332
EPS8L1 EPS8-like 1 2.2913
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.29024
INTS1 integrator complex subunit 1 2.28982
TLE6 transducin-like enhancer of split 6 2.28896
ACTN4 actinin, alpha 4 2.28741
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.28384
RAB21 RAB21, member RAS oncogene family 2.28143
ARL3 ADP-ribosylation factor-like 3 2.27958
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.27857
SIX3 SIX homeobox 3 2.27847
MARK4 MAP/microtubule affinity-regulating kinase 4 2.27728
RPE ribulose-5-phosphate-3-epimerase 2.27206
DCAF13 DDB1 and CUL4 associated factor 13 2.27074
NELL1 NEL-like 1 (chicken) 2.26905
MAGEB3 melanoma antigen family B3 2.26904
SARM1 sterile alpha and TIR motif containing 1 2.26824
ADAM2 ADAM metallopeptidase domain 2 2.26551
DENND2D DENN/MADD domain containing 2D 2.26428
CTNND1 catenin (cadherin-associated protein), delta 1 2.26414
HMG20B high mobility group 20B 2.25582
WDR46 WD repeat domain 46 2.2552
EXT1 exostosin glycosyltransferase 1 2.25434
CYB561 cytochrome b561 2.25097
TJP3 tight junction protein 3 2.2439
CXCL11 chemokine (C-X-C motif) ligand 11 2.24335
ITM2C integral membrane protein 2C 2.243
ZNF362 zinc finger protein 362 2.24237
TAGLN3 transgelin 3 2.24165
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 2.24002
SOX2 SRY (sex determining region Y)-box 2 2.23952
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 2.23878
SYNJ2BP synaptojanin 2 binding protein 2.23816
PRMT8 protein arginine methyltransferase 8 2.23783
CFAP298 cilia and flagella associated protein 298 2.23758
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 2.2374
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.23377
ADGRD2 adhesion G protein-coupled receptor D2 2.23359
GTF3A general transcription factor IIIA 2.23244
KIF26B kinesin family member 26B 2.23185
ACKR3 atypical chemokine receptor 3 2.22943
TAS2R9 taste receptor, type 2, member 9 2.22938
IMPACT impact RWD domain protein 2.22854
CD44 CD44 molecule (Indian blood group) 2.22853
JCAD junctional cadherin 5 associated 2.22302
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.22096
SERGEF secretion regulating guanine nucleotide exchange factor 2.22081
CNOT3 CCR4-NOT transcription complex, subunit 3 2.21954
GAS2L1 growth arrest-specific 2 like 1 2.219
PDAP1 PDGFA associated protein 1 2.21883
TP53TG5 TP53 target 5 2.21077
RGCC regulator of cell cycle 2.20764
ZBTB22 zinc finger and BTB domain containing 22 2.20699
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.20496
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.2049
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.2049
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.20474
TLX1 T-cell leukemia homeobox 1 2.20306
SART1 squamous cell carcinoma antigen recognized by T cells 2.20201
ARL2BP ADP-ribosylation factor-like 2 binding protein 2.20123
CNTNAP3B contactin associated protein-like 3B 2.19947
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.19886
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 2.19795
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.19774
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.19674
CLDN7 claudin 7 2.19445
TRIM15 tripartite motif containing 15 2.19434
FBXO7 F-box protein 7 2.19182
CLEC10A C-type lectin domain family 10, member A 2.19157
COL8A2 collagen, type VIII, alpha 2 2.19122
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.19086
VAV3 vav 3 guanine nucleotide exchange factor 2.19004
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.18973
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.18866
ARL15 ADP-ribosylation factor-like 15 2.18857
AOC1 amine oxidase, copper containing 1 2.18752
RUSC2 RUN and SH3 domain containing 2 2.1852
PTH2R parathyroid hormone 2 receptor 2.18508
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.18238
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.18051
PTPRC protein tyrosine phosphatase, receptor type, C 2.1783
TNNT3 troponin T type 3 (skeletal, fast) 2.17828
DSCC1 DNA replication and sister chromatid cohesion 1 2.1781
GAA glucosidase, alpha; acid 2.17749
IFT140 intraflagellar transport 140 2.17729
TBX6 T-box 6 2.17664
ZNF395 zinc finger protein 395 2.1766
PACS1 phosphofurin acidic cluster sorting protein 1 2.17402
PTPRU protein tyrosine phosphatase, receptor type, U 2.17295
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.17181
RB1 retinoblastoma 1 2.17177
PROCR protein C receptor, endothelial 2.17166
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.16792
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.1664
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 2.1655
PCDH17 protocadherin 17 2.16548
SYNGAP1 synaptic Ras GTPase activating protein 1 2.1644
BCO1 beta-carotene oxygenase 1 2.16401
STK10 serine/threonine kinase 10 2.1627
GHRH growth hormone releasing hormone 2.16269
ATF7 activating transcription factor 7 2.16252
RIPOR1 RHO family interacting cell polarization regulator 1 2.15873
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.15854
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.15828
GPALPP1 GPALPP motifs containing 1 2.15799
GALT galactose-1-phosphate uridylyltransferase 2.15651
TAS2R16 taste receptor, type 2, member 16 2.15604
CAV2 caveolin 2 2.15564
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.15514
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.15381
TBC1D30 TBC1 domain family, member 30 2.15376
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.15049
NACAD NAC alpha domain containing 2.15018
FSCN2 fascin actin-bundling protein 2, retinal 2.1501
NT5DC2 5'-nucleotidase domain containing 2 2.14829
RBM42 RNA binding motif protein 42 2.14759
RIMBP2 RIMS binding protein 2 2.14678
HRK harakiri, BCL2 interacting protein 2.14651
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.14608
SDK2 sidekick cell adhesion molecule 2 2.14606
CCRL2 chemokine (C-C motif) receptor-like 2 2.1454
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.14421
WRNIP1 Werner helicase interacting protein 1 2.14247
NTAN1 N-terminal asparagine amidase 2.14179
MYH9 myosin, heavy chain 9, non-muscle 2.14174
PTPRF protein tyrosine phosphatase, receptor type, F 2.14071
PLAAT2 phospholipase A and acyltransferase 2 2.13905
ADGRF1 adhesion G protein-coupled receptor F1 2.13838
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.13765
CDK5 cyclin-dependent kinase 5 2.13753
PYCR1 pyrroline-5-carboxylate reductase 1 2.13618
SPEG SPEG complex locus 2.13425
TSPAN12 tetraspanin 12 2.13261
FRK fyn-related Src family tyrosine kinase 2.13023
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 2.12877
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 2.12723
ALK anaplastic lymphoma receptor tyrosine kinase 2.12652
CD47 CD47 molecule 2.12449
RAB40B RAB40B, member RAS oncogene family 2.12443
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.12377
FJX1 four jointed box 1 (Drosophila) 2.12356
TLX2 T-cell leukemia homeobox 2 2.12251
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.12152
NRP1 neuropilin 1 2.12145
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.12063
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.11669
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.11616
ZNF804A zinc finger protein 804A 2.11552
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.11525
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.11512
CRIPTO3 cripto, EGF-CFC family member 3 2.11473
TRDMT1 tRNA aspartic acid methyltransferase 1 2.11412
ZMYM2 zinc finger, MYM-type 2 2.11251
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.11044
SORBS1 sorbin and SH3 domain containing 1 2.10922
SNX7 sorting nexin 7 2.10921
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 2.10913
TUBAL3 tubulin, alpha-like 3 2.10784
CYSLTR1 cysteinyl leukotriene receptor 1 2.1075
PRSS16 protease, serine, 16 (thymus) 2.10735
CRX cone-rod homeobox 2.107
A4GALT alpha 1,4-galactosyltransferase 2.10563
STK16 serine/threonine kinase 16 2.10545
GUK1 guanylate kinase 1 2.10537
HCAR3 hydroxycarboxylic acid receptor 3 2.10517
RANBP17 RAN binding protein 17 2.10515
HR hair growth associated 2.10477
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.10455
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.10366
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.10035
DHCR7 7-dehydrocholesterol reductase 2.09896
MARK1 MAP/microtubule affinity-regulating kinase 1 2.09865
MOB3B MOB kinase activator 3B 2.09844
NKX6-1 NK6 homeobox 1 2.09754
TLR3 toll-like receptor 3 2.09722
L1TD1 LINE-1 type transposase domain containing 1 2.09663
LAP3 leucine aminopeptidase 3 2.09578
CDIP1 cell death-inducing p53 target 1 2.09405
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.0913
HOMER3 homer scaffolding protein 3 2.09076
IGSF6 immunoglobulin superfamily, member 6 2.0898
ADIRF adipogenesis regulatory factor 2.08911
COL4A2 collagen, type IV, alpha 2 2.08873
CIB2 calcium and integrin binding family member 2 2.08798
TRIM46 tripartite motif containing 46 2.08741
HLX H2.0-like homeobox 2.08715
TRABD TraB domain containing 2.08304
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 2.08179
PICK1 protein interacting with PRKCA 1 2.08077
CUX2 cut-like homeobox 2 2.08069
LAMP3 lysosomal-associated membrane protein 3 2.08024
MTM1 myotubularin 1 2.08002
WDR13 WD repeat domain 13 2.07996
PDE5A phosphodiesterase 5A, cGMP-specific 2.07666
RUVBL1 RuvB-like AAA ATPase 1 2.07543
CEP72 centrosomal protein 72kDa 2.0744
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.07384
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.07214
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.07214
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.07145
ZNF532 zinc finger protein 532 2.07065
OCRL oculocerebrorenal syndrome of Lowe 2.07023
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 2.06929
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.06923
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.06903
TMEM184B transmembrane protein 184B 2.06834
OTULINL OTU deubiquitinase with linear linkage specificity like 2.06766
TRAPPC10 trafficking protein particle complex 10 2.06748
F11R F11 receptor 2.06702
INO80B INO80 complex subunit B 2.06672
NGB neuroglobin 2.06627
HOXC10 homeobox C10 2.06441
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.06436
PSENEN presenilin enhancer gamma secretase subunit 2.06359
SH2D3A SH2 domain containing 3A 2.06312
CCDC25 coiled-coil domain containing 25 2.06281
ULK1 unc-51 like autophagy activating kinase 1 2.06265
SAE1 SUMO1 activating enzyme subunit 1 2.06251
SPACA1 sperm acrosome associated 1 2.06123
ADGRF5 adhesion G protein-coupled receptor F5 2.06034
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 2.06023
PXDN peroxidasin 2.05786
BTG3 BTG family, member 3 2.05564
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.05556
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.05539
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.05426
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.05282
RAD21L1 RAD21-like 1 (S. pombe) 2.05241
BCAM basal cell adhesion molecule (Lutheran blood group) 2.05184
THSD4 thrombospondin, type I, domain containing 4 2.04933
RUFY1 RUN and FYVE domain containing 1 2.04904
NFU1 NFU1 iron-sulfur cluster scaffold 2.04862
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.04837
MYH14 myosin, heavy chain 14, non-muscle 2.04689
UPB1 ureidopropionase, beta 2.04529
GPR85 G protein-coupled receptor 85 2.04241
NR2F6 nuclear receptor subfamily 2, group F, member 6 2.04186
NOL10 nucleolar protein 10 2.04088
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.04081
CLDN14 claudin 14 2.03947
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.03925
PELP1 proline, glutamate and leucine rich protein 1 2.03884
PTH1R parathyroid hormone 1 receptor 2.03859
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.03739
LMAN1L lectin, mannose-binding, 1 like 2.0363
EDN1 endothelin 1 2.03578
ERC2 ELKS/RAB6-interacting/CAST family member 2 2.03571
POFUT2 protein O-fucosyltransferase 2 2.03538
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.03456
SNPH syntaphilin 2.03079
IQCC IQ motif containing C 2.02955
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 2.02946
TLN2 talin 2 2.02843
GIPC2 GIPC PDZ domain containing family, member 2 2.02759
WWC2 WW and C2 domain containing 2 2.02699
GSTA1 glutathione S-transferase alpha 1 2.0253
DUOX1 dual oxidase 1 2.02288
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 2.02213
MYO1F myosin IF 2.02139
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.0211
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.02072
CLCN7 chloride channel, voltage-sensitive 7 2.02058
CCDC144A coiled-coil domain containing 144A 2.01729
RAB31 RAB31, member RAS oncogene family 2.0168
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.01264
ZBED2 zinc finger, BED-type containing 2 2.01167
F8A2 coagulation factor VIII-associated 2 2.01142
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.01093
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 2.01071
SCRN3 secernin 3 2.01064
NOL6 nucleolar protein 6 (RNA-associated) 2.00981
TXNRD2 thioredoxin reductase 2 2.00904
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.00707
COPE coatomer protein complex, subunit epsilon 2.00597
LHX6 LIM homeobox 6 2.00351
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.00012

decreased expression

Symbol Name Standardized Value
IER3 immediate early response 3 -10.0
CDK7 cyclin-dependent kinase 7 -10.0
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -10.0
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -10.0
MYC v-myc avian myelocytomatosis viral oncogene homolog -10.0
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -9.84309
FASTKD5 FAST kinase domains 5 -9.38185
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -9.38053
TRIB1 tribbles pseudokinase 1 -9.25612
DUSP6 dual specificity phosphatase 6 -9.10395
GDF15 growth differentiation factor 15 -8.90967
TWF2 twinfilin actin binding protein 2 -8.6397
KHDC4 KH domain containing 4, pre-mRNA splicing factor -8.55899
NCK1 NCK adaptor protein 1 -8.19056
RFC2 replication factor C (activator 1) 2, 40kDa -7.70026
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -7.46596
RPP38 ribonuclease P/MRP 38kDa subunit -7.44239
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -7.25529
CASP3 caspase 3, apoptosis-related cysteine peptidase -7.14481
ZBTB35 zinc finger and BTB domain containing 35 -6.83034
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.49686
TXLNA taxilin alpha -6.49349
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -6.43454
FAT1 FAT atypical cadherin 1 -6.38286
DHRS7 dehydrogenase/reductase (SDR family) member 7 -6.28842
CDPF1 cysteine-rich, DPF motif domain containing 1 -6.27595
TCERG1 transcription elongation regulator 1 -6.26042
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.19998
PUF60 poly-U binding splicing factor 60KDa -6.14836
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -6.11064
NUP62 nucleoporin 62kDa -6.05837
NUP85 nucleoporin 85kDa -6.04793
TATDN2 TatD DNase domain containing 2 -5.88532
CD58 CD58 molecule -5.69317
ZW10 zw10 kinetochore protein -5.66707
DDIT4 DNA-damage-inducible transcript 4 -5.65226
KDM3A lysine (K)-specific demethylase 3A -5.52328
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.47074
C2CD5 C2 calcium-dependent domain containing 5 -5.42616
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -5.39579
HEATR1 HEAT repeat containing 1 -5.38441
TOP2A topoisomerase (DNA) II alpha 170kDa -5.34062
MELK maternal embryonic leucine zipper kinase -5.25615
AKAP8 A kinase (PRKA) anchor protein 8 -5.22665
EAPP E2F-associated phosphoprotein -5.12823
CDC20 cell division cycle 20 -4.88631
ATMIN ATM interactor -4.86376
ANKRD10 ankyrin repeat domain 10 -4.8416
MAT2A methionine adenosyltransferase II, alpha -4.73126
LBR lamin B receptor -4.63826
JMJD6 jumonji domain containing 6 -4.60513
TXNRD1 thioredoxin reductase 1 -4.5159
SPAG4 sperm associated antigen 4 -4.47761
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.45967
ZDHHC6 zinc finger, DHHC-type containing 6 -4.45032
KEAP1 kelch-like ECH-associated protein 1 -4.43373
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -4.21464
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.11932
RBM15B RNA binding motif protein 15B -4.10492
CDK1 cyclin-dependent kinase 1 -3.96325
THAP11 THAP domain containing 11 -3.84784
TUBB6 tubulin, beta 6 class V -3.7977
GOLT1B golgi transport 1B -3.77858
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.77091
TBPL1 TBP-like 1 -3.75348
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.73974
IER2 immediate early response 2 -3.73686
ADO 2-aminoethanethiol (cysteamine) dioxygenase -3.73277
MRPS2 mitochondrial ribosomal protein S2 -3.68978
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -3.67205
TCTN1 tectonic family member 1 -3.65888
RNF4 ring finger protein 4 -3.64549
AARS1 alanyl-tRNA synthetase 1 -3.63538
INPP1 inositol polyphosphate-1-phosphatase -3.58499
CAB39 calcium binding protein 39 -3.58198
RBM15 RNA binding motif protein 15 -3.58115
CLTC clathrin, heavy chain (Hc) -3.55298
ZMIZ1 zinc finger, MIZ-type containing 1 -3.54008
NRBF2 nuclear receptor binding factor 2 -3.52582
GLOD4 glyoxalase domain containing 4 -3.52185
PRPF38B pre-mRNA processing factor 38B -3.5116
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.50533
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.47828
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.4469
HOXA5 homeobox A5 -3.42998
EGR1 early growth response 1 -3.42155
PRDX1 peroxiredoxin 1 -3.41556
ADNP activity-dependent neuroprotector homeobox -3.4124
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.40346
RNMT RNA (guanine-7-) methyltransferase -3.39563
TEFM transcription elongation factor, mitochondrial -3.36909
SNX11 sorting nexin 11 -3.34344
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.31358
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.2976
ZCCHC8 zinc finger, CCHC domain containing 8 -3.28649
ZNF207 zinc finger protein 207 -3.26556
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -3.23918
COG7 component of oligomeric golgi complex 7 -3.21989
TRAF1 TNF receptor-associated factor 1 -3.19943
SESN1 sestrin 1 -3.19652
NISCH nischarin -3.13949
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -3.13277
BLCAP bladder cancer associated protein -3.117
EIF5 eukaryotic translation initiation factor 5 -3.09284
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -3.09212
ABT1 activator of basal transcription 1 -3.09167
MKNK2 MAP kinase interacting serine/threonine kinase 2 -3.08719
PLP1 proteolipid protein 1 -3.07996
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.07971
GGNBP2 gametogenetin binding protein 2 -3.07189
BCL10 B-cell CLL/lymphoma 10 -3.06637
SRC SRC proto-oncogene, non-receptor tyrosine kinase -3.06408
MKRN2 makorin ring finger protein 2 -3.054
NIT1 nitrilase 1 -3.04903
RPL36AL ribosomal protein L36a-like -3.04488
FZD7 frizzled class receptor 7 -3.04083
MFAP1 microfibrillar-associated protein 1 -3.01987
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.00347
SASH3 SAM and SH3 domain containing 3 -3.00105
ZNHIT3 zinc finger, HIT-type containing 3 -2.99689
CEP76 centrosomal protein 76kDa -2.99312
PRKCD protein kinase C, delta -2.98745
CCNA2 cyclin A2 -2.98443
ASDURF ASNSD1 upstream open reading frame -2.97795
ZBTB11 zinc finger and BTB domain containing 11 -2.97069
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.95359
BIRC2 baculoviral IAP repeat containing 2 -2.95281
COPB1 coatomer protein complex, subunit beta 1 -2.93873
PCNA proliferating cell nuclear antigen -2.93406
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.93403
SMG8 SMG8 nonsense mediated mRNA decay factor -2.93202
CASC3 cancer susceptibility candidate 3 -2.92935
MEX3C mex-3 RNA binding family member C -2.92415
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.92107
CHERP calcium homeostasis endoplasmic reticulum protein -2.90322
MED28 mediator complex subunit 28 -2.90275
AURKA aurora kinase A -2.89961
SEC24B SEC24 family member B -2.89646
VGLL4 vestigial-like family member 4 -2.89223
ZNF318 zinc finger protein 318 -2.87931
RBM6 RNA binding motif protein 6 -2.85486
ZNF143 zinc finger protein 143 -2.83413
HLA-DMA major histocompatibility complex, class II, DM alpha -2.83281
MSH6 mutS homolog 6 -2.82682
SETD5 SET domain containing 5 -2.80872
TDG thymine-DNA glycosylase -2.78998
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.77575
RIOK2 RIO kinase 2 -2.75705
ZDHHC7 zinc finger, DHHC-type containing 7 -2.74725
RAB9A RAB9A, member RAS oncogene family -2.74438
CANT1 calcium activated nucleotidase 1 -2.73929
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -2.73039
THUMPD1 THUMP domain containing 1 -2.72808
SPRY2 sprouty homolog 2 (Drosophila) -2.72606
LOC102724023 ES1 protein homolog, mitochondrial -2.70282
MAPK6 mitogen-activated protein kinase 6 -2.69623
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.69296
MVP major vault protein -2.6903
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.68554
ANKRD17 ankyrin repeat domain 17 -2.68224
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -2.68173
IP6K2 inositol hexakisphosphate kinase 2 -2.67586
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.67548
SCAF8 SR-related CTD-associated factor 8 -2.66808
FBXO34 F-box protein 34 -2.66521
ZNF586 zinc finger protein 586 -2.65952
FAM53C family with sequence similarity 53, member C -2.64845
VEZF1 vascular endothelial zinc finger 1 -2.64187
RBM14-RBM4 RBM14-RBM4 readthrough -2.63905
JPT1 Jupiter microtubule associated homolog 1 -2.63846
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.63142
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.62465
SNUPN snurportin 1 -2.622
ZNF443 zinc finger protein 443 -2.61751
IGHMBP2 immunoglobulin mu binding protein 2 -2.61477
FOSL1 FOS-like antigen 1 -2.60724
SDF2 stromal cell-derived factor 2 -2.60611
SEC16A SEC16 homolog A (S. cerevisiae) -2.60114
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.59696
ASTE1 asteroid homolog 1 (Drosophila) -2.59157
GTPBP8 GTP-binding protein 8 (putative) -2.58672
CRBN cereblon -2.57922
ARGLU1 arginine and glutamate rich 1 -2.57741
CYTH1 cytohesin 1 -2.57229
WDR82 WD repeat domain 82 -2.57094
IST1 increased sodium tolerance 1 homolog (yeast) -2.56576
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -2.55644
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.55549
ACOT9 acyl-CoA thioesterase 9 -2.55541
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.54953
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.53983
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -2.5294
TMEM11 transmembrane protein 11 -2.52125
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.5205
SPOP speckle-type POZ protein -2.51757
RNASE7 ribonuclease, RNase A family, 7 -2.5152
ZNF106 zinc finger protein 106 -2.51243
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.49525
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.4929
SPATA2 spermatogenesis associated 2 -2.49133
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -2.49066
ZFYVE16 zinc finger, FYVE domain containing 16 -2.48686
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.48317
SOX4 SRY (sex determining region Y)-box 4 -2.47791
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.4747
GRWD1 glutamate-rich WD repeat containing 1 -2.46453
GNAS GNAS complex locus -2.45934
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.45638
HMGXB4 HMG box domain containing 4 -2.43995
RGS2 regulator of G-protein signaling 2 -2.43712
PRUNE1 prune exopolyphosphatase 1 -2.42064
BCL6 B-cell CLL/lymphoma 6 -2.42047
PUM1 pumilio RNA-binding family member 1 -2.41917
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.40771
S100B S100 calcium binding protein B -2.40742
PLAGL2 pleiomorphic adenoma gene-like 2 -2.40456
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.40305
HSPA1A heat shock 70kDa protein 1A -2.39788
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -2.38783
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.38682
ARID4B AT rich interactive domain 4B (RBP1-like) -2.38185
CHSY1 chondroitin sulfate synthase 1 -2.37132
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -2.36016
EIF4H eukaryotic translation initiation factor 4H -2.3599
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -2.35782
RAB22A RAB22A, member RAS oncogene family -2.35353
GTF2B general transcription factor IIB -2.3454
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -2.34388
NRIP1 nuclear receptor interacting protein 1 -2.33984
FAM193A family with sequence similarity 193, member A -2.33551
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.32532
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.31813
ZNHIT6 zinc finger, HIT-type containing 6 -2.30886
SETX senataxin -2.30854
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.30431
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.30173
MED13 mediator complex subunit 13 -2.30164
SEC24A SEC24 family member A -2.29511
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.29002
PLAT plasminogen activator, tissue -2.28884
NUP42 nucleoporin 42 -2.28729
AFG3L2 AFG3-like AAA ATPase 2 -2.28699
TBC1D10C TBC1 domain family, member 10C -2.28537
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.28501
SSUH2 ssu-2 homolog (C. elegans) -2.28291
ZBTB24 zinc finger and BTB domain containing 24 -2.28251
RBM4B RNA binding motif protein 4B -2.2803
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.27898
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.27796
USP9X ubiquitin specific peptidase 9, X-linked -2.27762
ZCCHC24 zinc finger, CCHC domain containing 24 -2.27105
DCP2 decapping mRNA 2 -2.27081
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.25839
TTI2 TELO2 interacting protein 2 -2.25252
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -2.24671
VCPKMT valosin containing protein lysine (K) methyltransferase -2.24426
MGA MGA, MAX dimerization protein -2.23629
LPP LIM domain containing preferred translocation partner in lipoma -2.23453
SPPL2A signal peptide peptidase like 2A -2.23079
UBE3C ubiquitin protein ligase E3C -2.23072
SOX10 SRY (sex determining region Y)-box 10 -2.22886
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.2286
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.22255
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.22201
PUM2 pumilio RNA-binding family member 2 -2.21541
TMEM39A transmembrane protein 39A -2.21376
KMT5B lysine methyltransferase 5B -2.21124
NPTN neuroplastin -2.21057
HOMER1 homer scaffolding protein 1 -2.20844
HELZ helicase with zinc finger -2.20791
BAZ1A bromodomain adjacent to zinc finger domain, 1A -2.20627
MDN1 MDN1, midasin homolog (yeast) -2.20487
MRPL46 mitochondrial ribosomal protein L46 -2.20191
MED17 mediator complex subunit 17 -2.20114
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -2.19717
IQGAP2 IQ motif containing GTPase activating protein 2 -2.19698
KDM5A lysine (K)-specific demethylase 5A -2.19038
TM9SF2 transmembrane 9 superfamily member 2 -2.19034
ZZZ3 zinc finger, ZZ-type containing 3 -2.18992
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.18602
CHL1 cell adhesion molecule L1-like -2.18305
RBM12 RNA binding motif protein 12 -2.1824
SYNM synemin, intermediate filament protein -2.18132
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.17773
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.17688
ARCN1 archain 1 -2.17619
PGM1 phosphoglucomutase 1 -2.17361
LASP1 LIM and SH3 protein 1 -2.17292
MAK16 MAK16 homolog (S. cerevisiae) -2.17261
HAPSTR1 HUWE1 associated protein modifying stress responses -2.17247
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.17228
ZBED1 zinc finger, BED-type containing 1 -2.17068
FNBP4 formin binding protein 4 -2.16655
TMEM185B transmembrane protein 185B -2.16569
MARCHF7 membrane associated ring-CH-type finger 7 -2.16486
SIAH2 siah E3 ubiquitin protein ligase 2 -2.16231
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.15656
MT2A metallothionein 2A -2.14905
TOMM70 translocase of outer mitochondrial membrane 70 -2.14702
DCPH1 damage control phosphatase 1 -2.14628
CCNB2 cyclin B2 -2.1342
CAPN7 calpain 7 -2.12893
TGDS TDP-glucose 4,6-dehydratase -2.12798
MAGED1 melanoma antigen family D1 -2.12796
WDR37 WD repeat domain 37 -2.12634
SETMAR SET domain and mariner transposase fusion gene -2.12335
RBBP6 retinoblastoma binding protein 6 -2.12145
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.11805
FAM222B family with sequence similarity 222, member B -2.11247
NELFA negative elongation factor complex member A -2.11217
SECISBP2L SECIS binding protein 2-like -2.11207
SMNDC1 survival motor neuron domain containing 1 -2.10866
DCP1A decapping mRNA 1A -2.10864
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.10109
ZNF761 zinc finger protein 761 -2.10087
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.09082
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -2.07636
NUP153 nucleoporin 153kDa -2.07476
CNN1 calponin 1, basic, smooth muscle -2.07267
RAB7A RAB7A, member RAS oncogene family -2.06953
NOP14 NOP14 nucleolar protein -2.06417
SAR1B secretion associated, Ras related GTPase 1B -2.0593
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.05796
MAD2L1BP MAD2L1 binding protein -2.05598
ADIPOR2 adiponectin receptor 2 -2.0555
EMC6 ER membrane protein complex subunit 6 -2.05389
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.05307
ACTG2 actin, gamma 2, smooth muscle, enteric -2.04848
C5 complement component 5 -2.04759
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.04617
SKIC2 SKI2 subunit of superkiller complex -2.04604
SRP54 signal recognition particle 54kDa -2.04331
TASOR2 transcription activation suppressor family member 2 -2.04331
RBM4 RNA binding motif protein 4 -2.04073
GSPT2 G1 to S phase transition 2 -2.04065
TBC1D3G TBC1 domain family member 3G -2.03598
ZNF184 zinc finger protein 184 -2.03502
RBM39 RNA binding motif protein 39 -2.03494
BRIX1 BRX1, biogenesis of ribosomes -2.03367
CRLF3 cytokine receptor-like factor 3 -2.03321
FRYL FRY-like -2.0316
RBM7 RNA binding motif protein 7 -2.03157
NOP56 NOP56 ribonucleoprotein -2.02898
FXYD1 FXYD domain containing ion transport regulator 1 -2.0273
MBIP MAP3K12 binding inhibitory protein 1 -2.02691
TOP2B topoisomerase (DNA) II beta 180kDa -2.02443
KRT76 keratin 76, type II -2.02365
TGIF1 TGFB-induced factor homeobox 1 -2.02146
ZNF280A zinc finger protein 280A -2.02075
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.01671
TSC1 tuberous sclerosis 1 -2.01351
U2SURP U2 snRNP-associated SURP domain containing -2.01255
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -2.01189
NOP10 NOP10 ribonucleoprotein -2.01118
ZNF107 zinc finger protein 107 -2.01112
KIF2A kinesin heavy chain member 2A -2.00606
DNM1L dynamin 1-like -2.00557
SRRD SRR1 domain containing -2.004
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.00238