| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorocyclopentadiene 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN012_HEPG2_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.13586 |
| STIMATE | STIM activating enhancer | 5.8242 |
| CSK | c-src tyrosine kinase | 5.74685 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.03888 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.03605 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.27467 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.01638 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.94831 |
| PRR15L | proline rich 15-like | 3.74026 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.67756 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.55358 |
| PMM2 | phosphomannomutase 2 | 3.28402 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.25974 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.14342 |
| CHN1 | chimerin 1 | 3.0779 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.99245 |
| E2F2 | E2F transcription factor 2 | 2.83387 |
| MOK | MOK protein kinase | 2.80307 |
| LCN2 | lipocalin 2 | 2.79967 |
| PRKCH | protein kinase C, eta | 2.67202 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.62411 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.56678 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.56215 |
| CHMP6 | charged multivesicular body protein 6 | 2.48764 |
| IDE | insulin-degrading enzyme | 2.44147 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.34731 |
| CCNH | cyclin H | 2.31359 |
| CEP57 | centrosomal protein 57kDa | 2.29061 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.26882 |
| VWF | von Willebrand factor | 2.22185 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.20061 |
| KLHL9 | kelch-like family member 9 | 2.14413 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.07627 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.05661 |
| CCNF | cyclin F | 2.04311 |
| VASP | vasodilator-stimulated phosphoprotein | 2.03569 |
| KMT5B | lysine methyltransferase 5B | 2.02871 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.02215 |
| CHI3L2 | chitinase 3-like 2 | 2.01259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.88925 |
| YME1L1 | YME1-like 1 ATPase | -4.74358 |
| TLCD3A | TLC domain containing 3A | -4.2957 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.05016 |
| GDF15 | growth differentiation factor 15 | -4.04283 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.0378 |
| DNM1L | dynamin 1-like | -3.99437 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.747 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.71316 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.67232 |
| BLCAP | bladder cancer associated protein | -3.60216 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.50062 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.38157 |
| CCNB2 | cyclin B2 | -3.3321 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -3.15391 |
| HEATR1 | HEAT repeat containing 1 | -2.92152 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.6958 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.63379 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.59454 |
| UBE3C | ubiquitin protein ligase E3C | -2.56634 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.56417 |
| CDC20 | cell division cycle 20 | -2.44259 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.37123 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.36216 |
| VDAC1 | voltage-dependent anion channel 1 | -2.24877 |
| RAI14 | retinoic acid induced 14 | -2.24354 |
| PRPF18 | pre-mRNA processing factor 18 | -2.17717 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -2.16845 |
| WASHC4 | WASH complex subunit 4 | -2.14774 |
| RHEB | Ras homolog enriched in brain | -2.00436 |
| MTPAP | mitochondrial poly(A) polymerase | -2.00317 |
| SLFN12 | schlafen family member 12 | -2.00193 |
