| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenol 38.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN012_HEPG2_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 8.03705 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 7.87697 |
| CSK | c-src tyrosine kinase | 7.4857 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 6.19283 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.19917 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.23532 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.98657 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.64494 |
| STIMATE | STIM activating enhancer | 3.58294 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.57384 |
| CBR3 | carbonyl reductase 3 | 3.47955 |
| CHMP6 | charged multivesicular body protein 6 | 3.43165 |
| PFKL | phosphofructokinase, liver | 3.18705 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.95915 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 | 2.85803 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.8154 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.73946 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.67794 |
| NOSIP | nitric oxide synthase interacting protein | 2.59698 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 2.57547 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.49238 |
| MAP7 | microtubule-associated protein 7 | 2.48467 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 | 2.3065 |
| CYCS | cytochrome c, somatic | 2.2523 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 2.07653 |
| LEFTY2 | left-right determination factor 2 | 2.07584 |
| FGF1 | fibroblast growth factor 1 (acidic) | 2.07495 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 2.01606 |
| PLAC1 | placenta-specific 1 | 2.01346 |
| WNT2 | wingless-type MMTV integration site family member 2 | 2.00286 |
| TMEM121 | transmembrane protein 121 | 2.00188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.83393 |
| TLCD3A | TLC domain containing 3A | -4.33302 |
| VAT1 | vesicle amine transport 1 | -4.0555 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.02144 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.95844 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.61886 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.32224 |
| CCNB2 | cyclin B2 | -3.20047 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.13339 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.11196 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.94347 |
| ZNF586 | zinc finger protein 586 | -2.77234 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.74309 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.66067 |
| RAB13 | RAB13, member RAS oncogene family | -2.62952 |
| ELAC2 | elaC ribonuclease Z 2 | -2.59617 |
| RAI14 | retinoic acid induced 14 | -2.28307 |
| PCNA | proliferating cell nuclear antigen | -2.28086 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.17494 |
| RHEB | Ras homolog enriched in brain | -2.17371 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.15025 |
| GNAS | GNAS complex locus | -2.10048 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.01937 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -2.01299 |
