CRCGN012_HEPG2_24H:D14 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.98629
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
5.56711
|
|
UBQLN2
|
ubiquilin 2
|
4.94385
|
|
VGLL4
|
vestigial-like family member 4
|
4.64443
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.43941
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.22379
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.40607
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.25277
|
|
MMP1
|
matrix metallopeptidase 1
|
3.17925
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.11887
|
|
EPHB2
|
EPH receptor B2
|
3.02233
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.99851
|
|
PFKL
|
phosphofructokinase, liver
|
2.93415
|
|
CSK
|
c-src tyrosine kinase
|
2.79598
|
|
SFTPB
|
surfactant protein B
|
2.78979
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.59777
|
|
CDC45
|
cell division cycle 45
|
2.57412
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.4835
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.47281
|
|
MYLK
|
myosin light chain kinase
|
2.36979
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.28047
|
|
CEP57
|
centrosomal protein 57kDa
|
2.13493
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.1038
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.08908
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.0791
|
|
GATD3
|
glutamine amidotransferase class 1 domain containing 3
|
2.03793
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.02263
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.58452
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.95286
|
|
CCNB2
|
cyclin B2
|
-5.04642
|
|
CDC20
|
cell division cycle 20
|
-4.42397
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.30026
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.23668
|
|
SNX11
|
sorting nexin 11
|
-3.3104
|
|
JMJD6
|
jumonji domain containing 6
|
-2.62326
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.28674
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.26471
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.19789
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.19515
|
|
GSTT2B
|
glutathione S-transferase theta 2B (gene/pseudogene)
|
-2.13951
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.12925
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.11032
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.10924
|
|
CD58
|
CD58 molecule
|
-2.09474
|
