CRCGN012_HEPG2_24H:D16 Gene Set
Genes
49 genes differentially expressed following the CRCGN012_HEPG2_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
5.33593
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
5.15573
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.13005
|
|
STIMATE
|
STIM activating enhancer
|
4.19556
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.09016
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.81608
|
|
UBQLN2
|
ubiquilin 2
|
3.80757
|
|
NMU
|
neuromedin U
|
3.72026
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.4973
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.47458
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.4327
|
|
LCN2
|
lipocalin 2
|
3.22621
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.01358
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
2.75859
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.68631
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
2.63804
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.55906
|
|
CYCS
|
cytochrome c, somatic
|
2.29853
|
|
EPHA3
|
EPH receptor A3
|
2.23293
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.23168
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.11438
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.09516
|
|
BCHE
|
butyrylcholinesterase
|
2.06285
|
|
AP4M1
|
adaptor-related protein complex 4, mu 1 subunit
|
2.01761
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.00939
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
-6.03064
|
|
LDHD
|
lactate dehydrogenase D
|
-5.3892
|
|
MAP7
|
microtubule-associated protein 7
|
-5.08989
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.67433
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.26211
|
|
PLK1
|
polo-like kinase 1
|
-4.13546
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.03489
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.87601
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.86062
|
|
GOLT1B
|
golgi transport 1B
|
-3.4805
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.45273
|
|
MTA1
|
metastasis associated 1
|
-3.06851
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.97529
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.77843
|
|
MVP
|
major vault protein
|
-2.77339
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.67081
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.66383
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.51889
|
|
SNX11
|
sorting nexin 11
|
-2.49995
|
|
RAI14
|
retinoic acid induced 14
|
-2.43668
|
|
EGF
|
epidermal growth factor
|
-2.32142
|
|
CCNB2
|
cyclin B2
|
-2.30014
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.25062
|
|
TLN1
|
talin 1
|
-2.03816
|
