CRCGN012_HEPG2_24H:D17 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
8.35649
|
|
CYCS
|
cytochrome c, somatic
|
5.38121
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.0287
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.6947
|
|
ZNF589
|
zinc finger protein 589
|
4.62185
|
|
CBR3
|
carbonyl reductase 3
|
4.23773
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.12104
|
|
MYLK
|
myosin light chain kinase
|
4.06856
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.95163
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.60805
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.60201
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.21676
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.8799
|
|
TBP
|
TATA box binding protein
|
2.76783
|
|
KIF14
|
kinesin family member 14
|
2.73127
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.51458
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.4749
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.26835
|
|
GGCT
|
gamma-glutamylcyclotransferase
|
2.08274
|
|
ITIH2
|
inter-alpha-trypsin inhibitor heavy chain 2
|
2.04961
|
|
LIME1
|
Lck interacting transmembrane adaptor 1
|
2.022
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.66272
|
|
VAT1
|
vesicle amine transport 1
|
-6.20987
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-5.92939
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.83833
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.87182
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.80728
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-4.24402
|
|
MAP7
|
microtubule-associated protein 7
|
-4.14743
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.79826
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.74487
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.52886
|
|
DNM1L
|
dynamin 1-like
|
-3.45429
|
|
ZW10
|
zw10 kinetochore protein
|
-3.02101
|
|
WASHC4
|
WASH complex subunit 4
|
-2.88483
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.81821
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.52428
|
|
GNAS
|
GNAS complex locus
|
-2.47387
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.25469
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.0817
|
|
UBXN6
|
UBX domain protein 6
|
-2.07331
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.00309
|
