CRCGN012_HEPG2_24H:D18 Gene Set
Genes
34 genes differentially expressed following the CRCGN012_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
8.10225
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
6.34433
|
|
CBR3
|
carbonyl reductase 3
|
4.90512
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.73859
|
|
KLHL21
|
kelch-like family member 21
|
4.71001
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.54933
|
|
CSK
|
c-src tyrosine kinase
|
4.11659
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.84463
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.43389
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.43171
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.11162
|
|
IDE
|
insulin-degrading enzyme
|
2.84987
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.78745
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.65174
|
|
CHN1
|
chimerin 1
|
2.6397
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.34305
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.60144
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.90775
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.80392
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.49893
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-4.33591
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.19676
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.51163
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.35833
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-3.2016
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.16098
|
|
PEG10
|
paternally expressed 10
|
-2.45774
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.43953
|
|
GOLT1B
|
golgi transport 1B
|
-2.43655
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.3321
|
|
CCNB2
|
cyclin B2
|
-2.23722
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.22787
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.14377
|
|
VAT1
|
vesicle amine transport 1
|
-2.06187
|
