CRCGN012_HEPG2_24H:D23 Gene Set
Genes
32 genes differentially expressed following the CRCGN012_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
7.21159
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.31667
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.01608
|
|
SIRT3
|
sirtuin 3
|
3.95264
|
|
CSK
|
c-src tyrosine kinase
|
3.95182
|
|
EPHB2
|
EPH receptor B2
|
3.94835
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.79339
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.82968
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.71109
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.48589
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.47959
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.45813
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.31519
|
|
SV2C
|
synaptic vesicle glycoprotein 2C
|
2.05972
|
|
RPA3
|
replication protein A3, 14kDa
|
2.02648
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.94567
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.99627
|
|
AARS1
|
alanyl-tRNA synthetase 1
|
-4.95683
|
|
CCNB2
|
cyclin B2
|
-4.94297
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.29788
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.48376
|
|
CDC25B
|
cell division cycle 25B
|
-3.32528
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.02598
|
|
EGF
|
epidermal growth factor
|
-2.88006
|
|
GDF15
|
growth differentiation factor 15
|
-2.68782
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.56315
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.39816
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.26699
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.24667
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.22639
|
|
CCNH
|
cyclin H
|
-2.14451
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.04455
|
