CRCGN012_HEPG2_24H:E02 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
10.0
|
|
CSK
|
c-src tyrosine kinase
|
6.25834
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
4.15486
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.70922
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.55706
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.39575
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.32357
|
|
UBQLN2
|
ubiquilin 2
|
3.18598
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.17009
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.14774
|
|
STIMATE
|
STIM activating enhancer
|
2.88729
|
|
EVL
|
Enah/Vasp-like
|
2.8787
|
|
NOTCH1
|
notch 1
|
2.80981
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.75255
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.73198
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.73192
|
|
PRKCQ
|
protein kinase C, theta
|
2.7034
|
|
CDK6
|
cyclin-dependent kinase 6
|
2.59525
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.47433
|
|
TRIM13
|
tripartite motif containing 13
|
2.32072
|
|
VAT1
|
vesicle amine transport 1
|
2.28534
|
|
CBR3
|
carbonyl reductase 3
|
2.28518
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.18772
|
|
FZD7
|
frizzled class receptor 7
|
2.10736
|
|
NPR2
|
natriuretic peptide receptor 2
|
2.08153
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.02757
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.00992
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.94628
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.16514
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.14751
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.82055
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.61977
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.60501
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.29456
|
|
LDHD
|
lactate dehydrogenase D
|
-3.15346
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.02876
|
|
TBCB
|
tubulin folding cofactor B
|
-2.85382
|
|
LYPLA1
|
lysophospholipase I
|
-2.70407
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.67713
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.67665
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.44821
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.27441
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.1849
|
|
H2AB2
|
H2A.B variant histone 2
|
-2.05261
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.05007
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.0489
|
|
REEP5
|
receptor accessory protein 5
|
-2.03327
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.01399
|
