CRCGN012_HEPG2_24H:E04 Gene Set
Genes
52 genes differentially expressed following the CRCGN012_HEPG2_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.84954
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.66431
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.40482
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
6.09091
|
|
E2F2
|
E2F transcription factor 2
|
6.02151
|
|
CHN1
|
chimerin 1
|
4.02387
|
|
GPATCH8
|
G patch domain containing 8
|
3.99506
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.43499
|
|
UBQLN2
|
ubiquilin 2
|
3.4158
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.39279
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.35296
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.29128
|
|
MOK
|
MOK protein kinase
|
3.2476
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.21865
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.1982
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.14451
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
3.11791
|
|
HOXA10
|
homeobox A10
|
3.06897
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.0255
|
|
CSK
|
c-src tyrosine kinase
|
2.72678
|
|
NMU
|
neuromedin U
|
2.6336
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.56877
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.43721
|
|
KIF14
|
kinesin family member 14
|
2.39751
|
|
PTOV1
|
prostate tumor overexpressed 1
|
2.29623
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.23207
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.17618
|
|
HEBP1
|
heme binding protein 1
|
2.11268
|
|
CBR3
|
carbonyl reductase 3
|
2.0003
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.84181
|
|
MAP7
|
microtubule-associated protein 7
|
-3.98476
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.95062
|
|
DSG2
|
desmoglein 2
|
-3.75277
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.23434
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.22173
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.14543
|
|
CD58
|
CD58 molecule
|
-3.0189
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.87085
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.84663
|
|
CCNB2
|
cyclin B2
|
-2.84148
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.78071
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.75936
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.7375
|
|
CDC20
|
cell division cycle 20
|
-2.70975
|
|
LDHD
|
lactate dehydrogenase D
|
-2.64571
|
|
CCNB1
|
cyclin B1
|
-2.59217
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.55304
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.54919
|
|
SCAND1
|
SCAN domain containing 1
|
-2.3939
|
|
CAB39
|
calcium binding protein 39
|
-2.23258
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.21262
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.05092
|
