CRCGN012_HEPG2_24H:E08 Gene Set
Genes
33 genes differentially expressed following the CRCGN012_HEPG2_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.46647
|
|
NMU
|
neuromedin U
|
4.16321
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.02255
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.86572
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.72551
|
|
CSK
|
c-src tyrosine kinase
|
3.68934
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.39862
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.27483
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.23866
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.22315
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.12056
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.92211
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.36147
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.30125
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.28836
|
|
E2F2
|
E2F transcription factor 2
|
2.28793
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.24613
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.15915
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.0248
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.01612
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.28132
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.0186
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.49052
|
|
VAT1
|
vesicle amine transport 1
|
-3.33539
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.19026
|
|
HMG20B
|
high mobility group 20B
|
-2.94198
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.86822
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.8659
|
|
USP6NL
|
USP6 N-terminal like
|
-2.75284
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.57741
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.48386
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.3829
|
|
GPR137B
|
G protein-coupled receptor 137B
|
-2.09059
|
