CRCGN012_HEPG2_24H:E09 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.02241
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.74977
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.59778
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.49688
|
|
CISD1
|
CDGSH iron sulfur domain 1
|
4.43815
|
|
RPL39L
|
ribosomal protein L39-like
|
4.42525
|
|
CSK
|
c-src tyrosine kinase
|
3.81003
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.49722
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.25932
|
|
FAM20B
|
family with sequence similarity 20, member B
|
3.21056
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.11521
|
|
CRTAP
|
cartilage associated protein
|
2.52826
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.45948
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
2.42488
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.23087
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.20454
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.09853
|
|
TRAK2
|
trafficking protein, kinesin binding 2
|
2.00201
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-5.02631
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.60807
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.49343
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.43774
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.36686
|
|
LDHD
|
lactate dehydrogenase D
|
-4.26296
|
|
WASHC4
|
WASH complex subunit 4
|
-4.19006
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.16704
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.03009
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-3.27465
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.12961
|
|
GNAS
|
GNAS complex locus
|
-3.01932
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.01544
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.82766
|
|
FCHO1
|
FCH domain only 1
|
-2.79898
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.53183
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.4654
|
|
EGF
|
epidermal growth factor
|
-2.38325
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.09343
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.07308
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
-2.01101
|
