CRCGN012_HEPG2_24H:E14 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.50098
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
5.01441
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.92265
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.63603
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.58409
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.43982
|
|
CYCS
|
cytochrome c, somatic
|
3.55822
|
|
VGLL4
|
vestigial-like family member 4
|
3.01894
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.86752
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.76759
|
|
CEP57
|
centrosomal protein 57kDa
|
2.73915
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.64993
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.48734
|
|
E2F2
|
E2F transcription factor 2
|
2.42673
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.28095
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
2.23708
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.23439
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.20538
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.16232
|
|
NUCKS1
|
nuclear casein kinase and cyclin-dependent kinase substrate 1
|
2.03686
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.44194
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.92348
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.99837
|
|
GDF15
|
growth differentiation factor 15
|
-3.95542
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.96988
|
|
EGF
|
epidermal growth factor
|
-2.92688
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.90867
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.81299
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.60725
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.46255
|
|
BLCAP
|
bladder cancer associated protein
|
-2.44981
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.36602
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.31477
|
|
CD320
|
CD320 molecule
|
-2.21699
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.1054
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.03607
|
|
SQSTM1
|
sequestosome 1
|
-2.03499
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.02909
|
