| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cyclohexanone 5.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN012_HEPG2_24H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MSRA | methionine sulfoxide reductase A | 8.28331 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 8.04839 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.9573 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.79281 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 6.53266 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 6.38983 |
| CBR3 | carbonyl reductase 3 | 5.59134 |
| UBQLN2 | ubiquilin 2 | 4.89771 |
| GATA3 | GATA binding protein 3 | 4.87118 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.58447 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.20087 |
| ABHD6 | abhydrolase domain containing 6 | 3.80944 |
| LOC122526780 | uncharacterized LOC122526780 | 3.79174 |
| ATP11B | ATPase, class VI, type 11B | 3.46811 |
| CCNH | cyclin H | 3.37211 |
| PLS1 | plastin 1 | 3.21006 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.19466 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.15578 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.05462 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.86595 |
| E2F2 | E2F transcription factor 2 | 2.84081 |
| KIF14 | kinesin family member 14 | 2.81177 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.78896 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.73398 |
| TBXA2R | thromboxane A2 receptor | 2.49992 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 2.31705 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.24532 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.23589 |
| UFM1 | ubiquitin-fold modifier 1 | 2.20558 |
| RB1 | retinoblastoma 1 | 2.19502 |
| CDC25A | cell division cycle 25A | 2.13115 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 2.10559 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.00338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -9.68565 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.00714 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.91998 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.67837 |
| ADI1 | acireductone dioxygenase 1 | -4.36219 |
| CCDC86 | coiled-coil domain containing 86 | -3.39128 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.34154 |
| VAT1 | vesicle amine transport 1 | -3.293 |
| TLCD3A | TLC domain containing 3A | -3.28659 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.19633 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.19135 |
| CCNB2 | cyclin B2 | -3.16436 |
| CDC20 | cell division cycle 20 | -3.11822 |
| PCNA | proliferating cell nuclear antigen | -3.09758 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.788 |
| PDLIM1 | PDZ and LIM domain 1 | -2.74955 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.73331 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.71154 |
| LDHD | lactate dehydrogenase D | -2.70196 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -2.67616 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.6511 |
| HMOX1 | heme oxygenase 1 | -2.55337 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.22002 |
| LRRC41 | leucine rich repeat containing 41 | -2.11088 |
| MTX2 | metaxin 2 | -2.06795 |
| MRPL15 | mitochondrial ribosomal protein L15 | -2.05436 |
| RCOR3 | REST corepressor 3 | -2.01177 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein | -2.00169 |
