CRCGN012_HEPG2_24H:E17 Gene Set
Genes
41 genes differentially expressed following the CRCGN012_HEPG2_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
6.10188
|
|
CBR3
|
carbonyl reductase 3
|
5.5684
|
|
CCNA1
|
cyclin A1
|
3.87688
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.80083
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.79445
|
|
LCN2
|
lipocalin 2
|
3.61926
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.56561
|
|
JADE2
|
jade family PHD finger 2
|
3.27812
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.20636
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.19419
|
|
STK10
|
serine/threonine kinase 10
|
3.08742
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.96896
|
|
EVL
|
Enah/Vasp-like
|
2.72291
|
|
CDC45
|
cell division cycle 45
|
2.53817
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.47941
|
|
UBQLN2
|
ubiquilin 2
|
2.40493
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.30673
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.21821
|
|
CREB1
|
cAMP responsive element binding protein 1
|
2.12071
|
|
EPCAM
|
epithelial cell adhesion molecule
|
2.07543
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.00095
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.52196
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.58188
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.01968
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.84394
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.73468
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.65634
|
|
DNM1L
|
dynamin 1-like
|
-3.53914
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.49252
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.4564
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.39822
|
|
LDHD
|
lactate dehydrogenase D
|
-3.10353
|
|
CD320
|
CD320 molecule
|
-2.86486
|
|
RNF167
|
ring finger protein 167
|
-2.80356
|
|
WASHC4
|
WASH complex subunit 4
|
-2.78328
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.62025
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.42896
|
|
RBM34
|
RNA binding motif protein 34
|
-2.25826
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.19512
|
|
CDC20
|
cell division cycle 20
|
-2.16791
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.14827
|
