CRCGN012_HEPG2_24H:E18 Gene Set
Genes
53 genes differentially expressed following the CRCGN012_HEPG2_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.78352
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.73595
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
5.4627
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.54902
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
4.52573
|
|
KLHL21
|
kelch-like family member 21
|
4.23871
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.16772
|
|
NOTCH1
|
notch 1
|
3.81443
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
3.69852
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.67023
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.63392
|
|
CYCS
|
cytochrome c, somatic
|
3.36442
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.33604
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.22741
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.1335
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.88769
|
|
CCNF
|
cyclin F
|
2.86668
|
|
PFKL
|
phosphofructokinase, liver
|
2.85905
|
|
CHN1
|
chimerin 1
|
2.84922
|
|
UBQLN2
|
ubiquilin 2
|
2.32517
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.30938
|
|
JADE2
|
jade family PHD finger 2
|
2.17518
|
|
E2F2
|
E2F transcription factor 2
|
2.15642
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.14228
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.84161
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.2154
|
|
WASHC4
|
WASH complex subunit 4
|
-4.88731
|
|
DSG2
|
desmoglein 2
|
-4.75218
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.70301
|
|
DNM1L
|
dynamin 1-like
|
-4.63161
|
|
CCNB2
|
cyclin B2
|
-4.57687
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.37374
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.21691
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-4.18236
|
|
THAP11
|
THAP domain containing 11
|
-4.15845
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.80354
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-3.48442
|
|
LDHD
|
lactate dehydrogenase D
|
-3.33405
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.2492
|
|
CCNB1
|
cyclin B1
|
-3.24825
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.06967
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.94526
|
|
CRKL
|
v-crk avian sarcoma virus CT10 oncogene homolog-like
|
-2.7405
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.67911
|
|
SQSTM1
|
sequestosome 1
|
-2.63834
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.37399
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.33576
|
|
MVP
|
major vault protein
|
-2.30372
|
|
PPP2R5A
|
protein phosphatase 2, regulatory subunit B', alpha
|
-2.26758
|
|
THAP7
|
THAP domain containing 7
|
-2.14545
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-2.10592
|
|
TSPAN4
|
tetraspanin 4
|
-2.09124
|
|
CERK
|
ceramide kinase
|
-2.00096
|
