| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | telone ii 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN012_HEPG2_24H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 7.57283 |
| LPAR2 | lysophosphatidic acid receptor 2 | 5.38233 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.94225 |
| CHMP6 | charged multivesicular body protein 6 | 4.70592 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.58457 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.53512 |
| LCN2 | lipocalin 2 | 4.20102 |
| IDE | insulin-degrading enzyme | 3.92305 |
| CCNF | cyclin F | 3.86743 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.62848 |
| PFKL | phosphofructokinase, liver | 3.41886 |
| MOK | MOK protein kinase | 3.3381 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.91841 |
| MYLK | myosin light chain kinase | 2.91531 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.91303 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.71446 |
| PRR15L | proline rich 15-like | 2.67471 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.55933 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 2.31573 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.29955 |
| NMU | neuromedin U | 2.27187 |
| NOTCH1 | notch 1 | 2.23845 |
| DPEP1 | dipeptidase 1 (renal) | 2.23017 |
| E2F2 | E2F transcription factor 2 | 2.21233 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 2.19284 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.18604 |
| ICAM1 | intercellular adhesion molecule 1 | 2.11245 |
| S1PR4 | sphingosine-1-phosphate receptor 4 | 2.10862 |
| ZFP30 | ZFP30 zinc finger protein | 2.04878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.57458 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -7.24998 |
| MAP7 | microtubule-associated protein 7 | -5.50176 |
| TLCD3A | TLC domain containing 3A | -5.43907 |
| CCDC86 | coiled-coil domain containing 86 | -5.15111 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.8584 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.85347 |
| CDC25B | cell division cycle 25B | -3.63807 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.55395 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.29289 |
| THAP11 | THAP domain containing 11 | -3.25104 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.10125 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.91223 |
| ZNF586 | zinc finger protein 586 | -2.66159 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.61091 |
| SNX11 | sorting nexin 11 | -2.39455 |
| TRIB3 | tribbles pseudokinase 3 | -2.39192 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.30687 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.28717 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.12192 |
