CRCGN012_HEPG2_24H:E20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description telone ii 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

58 genes differentially expressed following the CRCGN012_HEPG2_24H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic 5.2335
RPL39L ribosomal protein L39-like 4.93654
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.63528
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.49072
SNAP25 synaptosomal-associated protein, 25kDa 4.44792
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.39384
STIMATE STIM activating enhancer 4.1063
CCL2 chemokine (C-C motif) ligand 2 3.99044
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.09114
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.92834
PFKL phosphofructokinase, liver 2.60197
TXNL4B thioredoxin-like 4B 2.52781
GATA3 GATA binding protein 3 2.47664
ANO1 anoctamin 1, calcium activated chloride channel 2.35249
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.32664
MGST3 microsomal glutathione S-transferase 3 2.28279
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.18484
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.16794
ADAT1 adenosine deaminase, tRNA-specific 1 2.13878
TM9SF2 transmembrane 9 superfamily member 2 2.11429

decreased expression

Symbol Name Standardized Value
UGDH UDP-glucose 6-dehydrogenase -4.71243
PLK1 polo-like kinase 1 -4.51197
TRIB3 tribbles pseudokinase 3 -4.43878
LDHD lactate dehydrogenase D -4.28336
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.22918
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.16424
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.0031
ZNF586 zinc finger protein 586 -3.93592
NISCH nischarin -3.87671
PRPF4 pre-mRNA processing factor 4 -3.79665
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.57093
EIF5 eukaryotic translation initiation factor 5 -3.49457
GNAS GNAS complex locus -3.35894
OXA1L oxidase (cytochrome c) assembly 1-like -3.32402
MTFR1 mitochondrial fission regulator 1 -3.25587
CCNB1 cyclin B1 -2.95245
PEG10 paternally expressed 10 -2.8998
ACAA1 acetyl-CoA acyltransferase 1 -2.78863
S100A3 S100 calcium binding protein A3 -2.7719
ZNF671 zinc finger protein 671 -2.76204
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.56657
EGF epidermal growth factor -2.52571
TRAPPC3 trafficking protein particle complex 3 -2.46274
ITGB1BP1 integrin beta 1 binding protein 1 -2.45182
IPO13 importin 13 -2.36003
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.34557
HROB homologous recombination factor with OB-fold -2.32198
GDF15 growth differentiation factor 15 -2.27771
IFRD2 interferon-related developmental regulator 2 -2.23434
FOLR3 folate receptor 3 (gamma) -2.14452
MEF2B myocyte enhancer factor 2B -2.10802
CTNND1 catenin (cadherin-associated protein), delta 1 -2.09913
PPOX protoporphyrinogen oxidase -2.09694
CNPY3-GNMT CNPY3-GNMT readthrough -2.08623
GPR12 G protein-coupled receptor 12 -2.07389
TCEAL2 transcription elongation factor A (SII)-like 2 -2.03714
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -2.00468
TSC1 tuberous sclerosis 1 -2.00377