CRCGN012_HEPG2_24H:E22 Gene Set
Genes
62 genes differentially expressed following the CRCGN012_HEPG2_24H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.61908
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.22292
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.17716
|
|
CSK
|
c-src tyrosine kinase
|
4.14286
|
|
PRR15L
|
proline rich 15-like
|
3.96938
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.44138
|
|
E2F2
|
E2F transcription factor 2
|
3.30851
|
|
CBR3
|
carbonyl reductase 3
|
3.22153
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.21643
|
|
LCN2
|
lipocalin 2
|
3.16687
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.15482
|
|
MYLK
|
myosin light chain kinase
|
3.11642
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.93403
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.83863
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.77594
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.77555
|
|
NUCB2
|
nucleobindin 2
|
2.67678
|
|
EPHA3
|
EPH receptor A3
|
2.64155
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.62276
|
|
STIMATE
|
STIM activating enhancer
|
2.6158
|
|
CHN1
|
chimerin 1
|
2.58927
|
|
NOTCH1
|
notch 1
|
2.57017
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.23559
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.19848
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
2.16998
|
|
CD82
|
CD82 molecule
|
2.1189
|
|
NPC2
|
Niemann-Pick disease, type C2
|
2.06031
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.04734
|
|
CCNF
|
cyclin F
|
2.04519
|
|
CYCS
|
cytochrome c, somatic
|
2.04283
|
|
SFTPB
|
surfactant protein B
|
2.00002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
GDF15
|
growth differentiation factor 15
|
-6.4035
|
|
EGF
|
epidermal growth factor
|
-4.09853
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.98898
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.91412
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.88855
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.85241
|
|
CDC20
|
cell division cycle 20
|
-3.60752
|
|
CCNB1
|
cyclin B1
|
-3.51631
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.44051
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.3981
|
|
ZNF586
|
zinc finger protein 586
|
-3.30769
|
|
DNM1L
|
dynamin 1-like
|
-3.21689
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.07087
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.96066
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.63847
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.57292
|
|
NVL
|
nuclear VCP-like
|
-2.33133
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.30168
|
|
NLRP2
|
NLR family, pyrin domain containing 2
|
-2.24013
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.21347
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.16034
|
|
TMEM109
|
transmembrane protein 109
|
-2.15289
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.14809
|
|
SCAND1
|
SCAN domain containing 1
|
-2.11246
|
|
SNX2
|
sorting nexin 2
|
-2.08364
|
|
NBEAL2
|
neurobeachin-like 2
|
-2.0771
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.02231
|
|
REEP5
|
receptor accessory protein 5
|
-2.01975
|
|
PTPRE
|
protein tyrosine phosphatase, receptor type, E
|
-2.0094
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.00919
|
