CRCGN012_HEPG2_24H:E23 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
10.0
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.9886
|
|
NOTCH1
|
notch 1
|
5.8468
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.61273
|
|
CSK
|
c-src tyrosine kinase
|
5.00732
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
4.56136
|
|
E2F2
|
E2F transcription factor 2
|
3.965
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.92171
|
|
JADE2
|
jade family PHD finger 2
|
3.61401
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.607
|
|
SATB1
|
SATB homeobox 1
|
3.5593
|
|
PRKCH
|
protein kinase C, eta
|
2.86714
|
|
CHN1
|
chimerin 1
|
2.79498
|
|
NENF
|
neudesin neurotrophic factor
|
2.73688
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.7349
|
|
LCN2
|
lipocalin 2
|
2.66323
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.61048
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.55033
|
|
TEX10
|
testis expressed 10
|
2.54354
|
|
PRR15L
|
proline rich 15-like
|
2.38638
|
|
FZD7
|
frizzled class receptor 7
|
2.36953
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.35391
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.23374
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.20012
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.05161
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.05105
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.03418
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.70489
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.84981
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.54854
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.47394
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.24459
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.99544
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.94792
|
|
CD320
|
CD320 molecule
|
-2.55256
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.54014
|
|
TBCB
|
tubulin folding cofactor B
|
-2.40332
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.33384
|
|
CD58
|
CD58 molecule
|
-2.25764
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.03737
|
|
TMEM147
|
transmembrane protein 147
|
-2.03435
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.02674
|
