CRCGN012_HEPG2_24H:E24 Gene Set
Genes
53 genes differentially expressed following the CRCGN012_HEPG2_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
10.0
|
|
LCN2
|
lipocalin 2
|
6.77094
|
|
VGLL4
|
vestigial-like family member 4
|
4.07547
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.95453
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.89172
|
|
RPL39L
|
ribosomal protein L39-like
|
3.83496
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.72399
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.52065
|
|
EPHA3
|
EPH receptor A3
|
3.31265
|
|
CHN1
|
chimerin 1
|
3.30138
|
|
CSK
|
c-src tyrosine kinase
|
3.24443
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.08471
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.99252
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.86748
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.78953
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.68171
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.6288
|
|
LAGE3
|
L antigen family, member 3
|
2.61695
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.56104
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.49555
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.47055
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.32315
|
|
PMM2
|
phosphomannomutase 2
|
2.3156
|
|
LTF
|
lactotransferrin
|
2.17499
|
|
CYCS
|
cytochrome c, somatic
|
2.15862
|
|
PHYH
|
phytanoyl-CoA 2-hydroxylase
|
2.11673
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.0888
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.84609
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.50795
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.18505
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.18324
|
|
GDF15
|
growth differentiation factor 15
|
-3.71314
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.47532
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.426
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.2653
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.04927
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.91163
|
|
CAB39
|
calcium binding protein 39
|
-2.63804
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.56951
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.56435
|
|
SNX11
|
sorting nexin 11
|
-2.51804
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.39535
|
|
CCNB2
|
cyclin B2
|
-2.28311
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.23024
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.2273
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.20927
|
|
TSPAN4
|
tetraspanin 4
|
-2.20202
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.16914
|
|
INSIG2
|
insulin induced gene 2
|
-2.16106
|
|
PRDM16
|
PR domain containing 16
|
-2.06678
|
|
TPGS1
|
tubulin polyglutamylase complex subunit 1
|
-2.04673
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.01573
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.00568
|
