| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | budesonide 21.37 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN012_HEPG2_24H:F01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 6.51985 |
| LCN2 | lipocalin 2 | 4.85358 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 3.89591 |
| MCOLN1 | mucolipin 1 | 3.85159 |
| NOSIP | nitric oxide synthase interacting protein | 3.63376 |
| CSK | c-src tyrosine kinase | 3.51986 |
| MYLK | myosin light chain kinase | 3.44344 |
| DDIT4 | DNA-damage-inducible transcript 4 | 3.28258 |
| NMU | neuromedin U | 3.15483 |
| KIFBP | kinesin family binding protein | 2.958 |
| CTSL | cathepsin L | 2.91165 |
| UBQLN2 | ubiquilin 2 | 2.89383 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.8745 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.71482 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.70913 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2.6371 |
| HOXA10 | homeobox A10 | 2.58726 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.5539 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.53595 |
| CCDC86 | coiled-coil domain containing 86 | 2.50873 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.45319 |
| STXBP1 | syntaxin binding protein 1 | 2.40246 |
| LOC122526780 | uncharacterized LOC122526780 | 2.27643 |
| HOMER2 | homer scaffolding protein 2 | 2.27049 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.26621 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.23446 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.23246 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.07763 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 2.06184 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.0349 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -4.09908 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.78974 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -3.7217 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.52307 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.46001 |
| CCNB2 | cyclin B2 | -3.41725 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.28056 |
| ZNF586 | zinc finger protein 586 | -3.23598 |
| CHMP4B | charged multivesicular body protein 4B | -3.22037 |
| UBE3C | ubiquitin protein ligase E3C | -3.20919 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.15709 |
| GLOD4 | glyoxalase domain containing 4 | -3.0467 |
| ALDOC | aldolase C, fructose-bisphosphate | -3.03689 |
| IER3 | immediate early response 3 | -3.03135 |
| TCTN1 | tectonic family member 1 | -2.91779 |
| SLC35F2 | solute carrier family 35, member F2 | -2.89224 |
| PDLIM1 | PDZ and LIM domain 1 | -2.88179 |
| CDC42 | cell division cycle 42 | -2.81553 |
| CD320 | CD320 molecule | -2.76967 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.56614 |
| SOAT2 | sterol O-acyltransferase 2 | -2.52615 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.27203 |
| TRIB3 | tribbles pseudokinase 3 | -2.22508 |
| VDAC1 | voltage-dependent anion channel 1 | -2.20833 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.20745 |
| PUDP | pseudouridine 5'-phosphatase | -2.1464 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.12231 |
| PNPO | pyridoxamine 5'-phosphate oxidase | -2.10984 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) | -2.08212 |
| CHEK1 | checkpoint kinase 1 | -2.03512 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -2.03242 |
