CRCGN012_HEPG2_24H:F06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description budesonide 0.67 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

70 genes differentially expressed following the CRCGN012_HEPG2_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 6.7019
NOSIP nitric oxide synthase interacting protein 4.55278
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.7396
E2F2 E2F transcription factor 2 3.64468
CYCS cytochrome c, somatic 3.56818
RPL39L ribosomal protein L39-like 3.5142
STIMATE STIM activating enhancer 3.39063
PEX11A peroxisomal biogenesis factor 11 alpha 3.37904
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.29011
SIRT3 sirtuin 3 3.09449
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.95679
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.88314
DDIT4 DNA-damage-inducible transcript 4 2.81329
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.75861
TBC1D31 TBC1 domain family, member 31 2.73823
SNAP25 synaptosomal-associated protein, 25kDa 2.72779
GPATCH8 G patch domain containing 8 2.67094
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.59662
DENND2D DENN/MADD domain containing 2D 2.58768
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.54964
DYNLT3 dynein, light chain, Tctex-type 3 2.47775
TIAM1 T-cell lymphoma invasion and metastasis 1 2.39207
SFTPB surfactant protein B 2.37943
PPARG peroxisome proliferator-activated receptor gamma 2.30386
CTSL cathepsin L 2.26925
CHI3L2 chitinase 3-like 2 2.25167
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.23624
SPTSSA serine palmitoyltransferase, small subunit A 2.22746
CCDC86 coiled-coil domain containing 86 2.17472
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.14498
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.12604
GTPBP8 GTP-binding protein 8 (putative) 2.12269
CCNF cyclin F 2.11803
FZD7 frizzled class receptor 7 2.11745
RIC8A RIC8 guanine nucleotide exchange factor A 2.11365
GPR22 G protein-coupled receptor 22 2.091
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.05455
IL32 interleukin 32 2.0339
MAST2 microtubule associated serine/threonine kinase 2 2.03242
B2M beta-2-microglobulin 2.02257
MBNL1 muscleblind-like splicing regulator 1 2.01699
CA3 carbonic anhydrase III 2.0116
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 2.0066

decreased expression

Symbol Name Standardized Value
KDM3A lysine (K)-specific demethylase 3A -6.74846
CDC20 cell division cycle 20 -6.64961
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.34924
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.13287
ADI1 acireductone dioxygenase 1 -3.64574
LAP3 leucine aminopeptidase 3 -3.61112
DSG2 desmoglein 2 -3.57449
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.30447
GDF15 growth differentiation factor 15 -3.26869
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.21432
MAPK13 mitogen-activated protein kinase 13 -3.16408
HSPB1 heat shock 27kDa protein 1 -2.97467
DUSP6 dual specificity phosphatase 6 -2.93175
RPN1 ribophorin I -2.74801
ZNF586 zinc finger protein 586 -2.73041
ZDHHC6 zinc finger, DHHC-type containing 6 -2.69426
TXNRD1 thioredoxin reductase 1 -2.67911
ZMIZ1 zinc finger, MIZ-type containing 1 -2.41921
VDAC1 voltage-dependent anion channel 1 -2.36211
SNX11 sorting nexin 11 -2.30799
UBE3C ubiquitin protein ligase E3C -2.26077
CEP131 centrosomal protein 131kDa -2.25628
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.19738
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.16761
EIF5 eukaryotic translation initiation factor 5 -2.11361
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.10677
PROSER1 proline and serine rich 1 -2.00918