CRCGN012_HEPG2_24H:F07 Gene Set
Genes
51 genes differentially expressed following the CRCGN012_HEPG2_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
8.398
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.35932
|
|
CYCS
|
cytochrome c, somatic
|
5.40145
|
|
E2F2
|
E2F transcription factor 2
|
4.5928
|
|
CSK
|
c-src tyrosine kinase
|
4.54436
|
|
CBR3
|
carbonyl reductase 3
|
4.35924
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.30568
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.23633
|
|
UBQLN2
|
ubiquilin 2
|
3.79893
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.69144
|
|
CHN1
|
chimerin 1
|
3.22161
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.86391
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.72905
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.64267
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.41989
|
|
PTK2
|
protein tyrosine kinase 2
|
2.41888
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.4096
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.36635
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.32406
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.28073
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.27348
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.25874
|
|
ZNF589
|
zinc finger protein 589
|
2.24312
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.21301
|
|
FCHO1
|
FCH domain only 1
|
2.17923
|
|
TEFM
|
transcription elongation factor, mitochondrial
|
2.15213
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.1383
|
|
LCN2
|
lipocalin 2
|
2.1045
|
|
PMM2
|
phosphomannomutase 2
|
2.08021
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.7173
|
|
CDC20
|
cell division cycle 20
|
-5.60956
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.21763
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.67858
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.52284
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.33996
|
|
GNAS
|
GNAS complex locus
|
-4.29595
|
|
ZNF586
|
zinc finger protein 586
|
-4.27203
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.24919
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.06294
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-3.9145
|
|
VAT1
|
vesicle amine transport 1
|
-3.7564
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.31651
|
|
CD320
|
CD320 molecule
|
-2.35908
|
|
PLEKHG6
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
|
-2.18226
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.16349
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.16319
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.16155
|
|
APOD
|
apolipoprotein D
|
-2.13126
|
|
NVL
|
nuclear VCP-like
|
-2.08354
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.06563
|
|
CD177
|
CD177 molecule
|
-2.06489
|
