CRCGN012_HEPG2_24H:F08 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
7.83361
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.26338
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.47993
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.44108
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.40936
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.1938
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.99833
|
|
MYLK
|
myosin light chain kinase
|
3.88012
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.64251
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.40683
|
|
NOTCH1
|
notch 1
|
3.26885
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.25635
|
|
STIMATE
|
STIM activating enhancer
|
3.15081
|
|
CHN1
|
chimerin 1
|
2.77627
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.74044
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.64581
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.63711
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.36027
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.33147
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32919
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.3165
|
|
CWC25
|
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
|
2.14702
|
|
CYCS
|
cytochrome c, somatic
|
2.06865
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.02848
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.48576
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.2031
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.63652
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-3.31638
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.3046
|
|
MRPL12
|
mitochondrial ribosomal protein L12
|
-3.28504
|
|
LDHD
|
lactate dehydrogenase D
|
-3.23285
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.23181
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.02269
|
|
GNAS
|
GNAS complex locus
|
-2.48586
|
|
SOX17
|
SRY (sex determining region Y)-box 17
|
-2.44649
|
|
CDC25B
|
cell division cycle 25B
|
-2.44215
|
|
ZNF586
|
zinc finger protein 586
|
-2.42865
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.40763
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-2.34621
|
|
CCNB2
|
cyclin B2
|
-2.30402
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.24883
|
|
HAT1
|
histone acetyltransferase 1
|
-2.24532
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.20272
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.14555
|
|
TES
|
testin LIM domain protein
|
-2.06884
|
|
PLEKHO1
|
pleckstrin homology domain containing, family O member 1
|
-2.06693
|
