CRCGN012_HEPG2_24H:F10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

50 genes differentially expressed following the CRCGN012_HEPG2_24H:F10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 6.33174
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 6.19359
MAMLD1 mastermind-like domain containing 1 4.39173
C2CD2 C2 calcium-dependent domain containing 2 4.28851
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.25867
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.16189
PNKP polynucleotide kinase 3'-phosphatase 4.12382
ADRB2 adrenoceptor beta 2, surface 4.12308
MEF2C myocyte enhancer factor 2C 3.73449
STIMATE STIM activating enhancer 3.61591
CXCL2 chemokine (C-X-C motif) ligand 2 3.57499
STK10 serine/threonine kinase 10 3.39033
CHMP6 charged multivesicular body protein 6 3.37623
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.37559
NOTCH1 notch 1 3.36154
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.24047
EVL Enah/Vasp-like 3.22851
ANO1 anoctamin 1, calcium activated chloride channel 3.08
PFKL phosphofructokinase, liver 2.64156
LOC122526780 uncharacterized LOC122526780 2.56209
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.53103
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.3169
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.24383
JADE2 jade family PHD finger 2 2.22373
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.18101
TIAM1 T-cell lymphoma invasion and metastasis 1 2.12341
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.08229
CHN1 chimerin 1 2.03496

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -7.91437
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.10447
MRPS2 mitochondrial ribosomal protein S2 -3.89149
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.59058
DNM1L dynamin 1-like -3.49608
EGF epidermal growth factor -3.40836
KDM3A lysine (K)-specific demethylase 3A -3.38685
ADI1 acireductone dioxygenase 1 -3.38048
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.36467
PRPF4 pre-mRNA processing factor 4 -3.35516
NGRN neugrin, neurite outgrowth associated -3.31583
UGDH UDP-glucose 6-dehydrogenase -3.25233
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.10238
ITGB1BP1 integrin beta 1 binding protein 1 -2.88329
PCNA proliferating cell nuclear antigen -2.7769
CDC20 cell division cycle 20 -2.69328
SNX11 sorting nexin 11 -2.68785
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.4772
CCDC86 coiled-coil domain containing 86 -2.42767
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.37498
RFC2 replication factor C (activator 1) 2, 40kDa -2.3551
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -2.03908