CRCGN012_HEPG2_24H:F11 Gene Set
Genes
37 genes differentially expressed following the CRCGN012_HEPG2_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.122
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.93101
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.79072
|
|
MYLK
|
myosin light chain kinase
|
2.9625
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.89859
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.75247
|
|
CYCS
|
cytochrome c, somatic
|
2.70633
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.45344
|
|
PRKCH
|
protein kinase C, eta
|
2.44205
|
|
NOTCH1
|
notch 1
|
2.41629
|
|
H2BC12
|
H2B clustered histone 12
|
2.36386
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.15194
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.13377
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.10693
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.0583
|
|
CCNB2
|
cyclin B2
|
-4.05992
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.91248
|
|
VAT1
|
vesicle amine transport 1
|
-3.85163
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.64145
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.48144
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-3.44353
|
|
BLVRA
|
biliverdin reductase A
|
-3.2429
|
|
MAP7
|
microtubule-associated protein 7
|
-3.11045
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.5571
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.50883
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.46099
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.40277
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.38018
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.37599
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.36309
|
|
SNX11
|
sorting nexin 11
|
-2.32903
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.30724
|
|
LYPLA1
|
lysophospholipase I
|
-2.27809
|
|
CSNK1E
|
casein kinase 1, epsilon
|
-2.26505
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.26358
|
|
MVP
|
major vault protein
|
-2.2321
|
|
DNM1L
|
dynamin 1-like
|
-2.00104
|
