CRCGN012_HEPG2_24H:F12 Gene Set
Genes
54 genes differentially expressed following the CRCGN012_HEPG2_24H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
8.65446
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
8.15263
|
|
MYLK
|
myosin light chain kinase
|
4.98023
|
|
STIMATE
|
STIM activating enhancer
|
4.90838
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.68295
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.37281
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.24974
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.10393
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.09741
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.09503
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.04781
|
|
UBQLN2
|
ubiquilin 2
|
4.03374
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.97693
|
|
CSK
|
c-src tyrosine kinase
|
3.86884
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.85768
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.63243
|
|
NOTCH1
|
notch 1
|
3.59266
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.5693
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.11248
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.09476
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.97807
|
|
GPATCH8
|
G patch domain containing 8
|
2.88704
|
|
PMM2
|
phosphomannomutase 2
|
2.80479
|
|
GATA3
|
GATA binding protein 3
|
2.59969
|
|
ZNF589
|
zinc finger protein 589
|
2.38794
|
|
CYCS
|
cytochrome c, somatic
|
2.36157
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.29729
|
|
CCNH
|
cyclin H
|
2.19986
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.39596
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.99932
|
|
CD320
|
CD320 molecule
|
-4.61479
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.46799
|
|
PEG10
|
paternally expressed 10
|
-4.45388
|
|
CCNB2
|
cyclin B2
|
-4.22689
|
|
FHL2
|
four and a half LIM domains 2
|
-4.02646
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.95885
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.68042
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.50154
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.34578
|
|
GNAS
|
GNAS complex locus
|
-3.25754
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.10053
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.06713
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.90812
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.69009
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.56393
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.51954
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.51818
|
|
HMG20B
|
high mobility group 20B
|
-2.4337
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.37642
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.23373
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.22257
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.13953
|
|
CDC25B
|
cell division cycle 25B
|
-2.06467
|
|
VIM
|
vimentin
|
-2.05505
|
