CRCGN012_HEPG2_24H:F13 Gene Set
Genes
57 genes differentially expressed following the CRCGN012_HEPG2_24H:F13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
7.2493
|
|
NOTCH1
|
notch 1
|
5.47
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.42104
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.14223
|
|
CSK
|
c-src tyrosine kinase
|
4.02838
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.78611
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.71212
|
|
RPL39L
|
ribosomal protein L39-like
|
3.47665
|
|
PRR15L
|
proline rich 15-like
|
3.37168
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.18852
|
|
LCN2
|
lipocalin 2
|
3.05573
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.91236
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.91122
|
|
TBP
|
TATA box binding protein
|
2.90354
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.87868
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.80384
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.78488
|
|
UBQLN2
|
ubiquilin 2
|
2.5392
|
|
BLMH
|
bleomycin hydrolase
|
2.4809
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.41656
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.36829
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.26677
|
|
CDC45
|
cell division cycle 45
|
2.16782
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.13276
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.10681
|
|
EPN2
|
epsin 2
|
2.07998
|
|
RNPS1
|
RNA binding protein S1, serine-rich domain
|
2.01048
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.89944
|
|
TRIB3
|
tribbles pseudokinase 3
|
-6.32863
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.22545
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.16042
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.90558
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.19782
|
|
GDF15
|
growth differentiation factor 15
|
-4.67355
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.28874
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.22592
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.42897
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.34715
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.11397
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.07744
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.04481
|
|
FBXO7
|
F-box protein 7
|
-2.87466
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.71045
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.65899
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.64308
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.62859
|
|
LDHD
|
lactate dehydrogenase D
|
-2.60043
|
|
CPNE3
|
copine III
|
-2.41954
|
|
GNAS
|
GNAS complex locus
|
-2.23871
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.19013
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.18517
|
|
BLCAP
|
bladder cancer associated protein
|
-2.18026
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.14414
|
|
CCNB1
|
cyclin B1
|
-2.13408
|
|
MVP
|
major vault protein
|
-2.11575
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.03784
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.02576
|
